Cent Eur J Public Health 1995, 3(2):65-66

Studies on immunomodulatory properties of isoniazid. Influence of isoniazid on responsiveness of peripheral blood mononuclear cells to interleukin-2

Kucharz E.J.
Fourth Department of Internal Medicine, Silesian University School of Medicine, Katowice, Poland

Peripheral blood mononuclear cells which were "resting" i.e. interleukin-2-receptor-negative were stimulated to proliferate by interleukin-2 in vitro. It was found that isoniazid at concentration of 10(-5)-10(-6) M increased the peak proliferation of "resting" cells but had no influence on the kinetics of proliferation. The mechanism of this effect of isoniazid remains unclear.

Published: May 1, 1995  Show citation

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Kucharz EJ. Studies on immunomodulatory properties of isoniazid. Influence of isoniazid on responsiveness of peripheral blood mononuclear cells to interleukin-2. Cent Eur J Public Health. 1995;3(2):65-66. PubMed PMID: 7655406.
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