Cent Eur J Public Health 2000, 8(Supplement):S66-S67

Results of the general toxicity and genetic studies of an insecticide intermediate

Béres E.1, Pasics I.1, Pap L.2, Hirka G.3, Sebestyén I.3, Oláh B.3, Stáhl J.3
1 Szakonyi Toxicological Research Centre Ltd., Veszprém, Hungary
2 Agro-Chemie Ltd., Budapest, Hungary
3 Toxicological Research Centre Ltd., Veszprém, Hungary

Methyl-chrysanthemate is one of the intermediates of pyrethroid type insecticides. The acute toxicity of the test item was investigated in rats after single oral, dermal and inhalation applications. The irritation effect was determined by Draize method. Buehler method was applied to evaluate the sensitization potential of the test item. The mutagenic effect was assessed on Salmonella typhimurium strains. Furthermore metaphase chromosome aberration assay was performed on CHO cell line to check the structural chromosome aberrations.

Zveřejněno: 1. červenec 2000  Zobrazit citaci

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Béres E, Pasics I, Pap L, Hirka G, Sebestyén I, Oláh B, Stáhl J. Results of the general toxicity and genetic studies of an insecticide intermediate. Cent Eur J Public Health. 2000;8(Supplement):S66-67. PubMed PMID: 10943473.
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