Cent Eur J Public Health 2004, 12(Supplement):S16-S18

Kojic Acid and its Derivatives: History and Present State of Art

Brtko J.1, Rondahl L.1, Ficková M.1, Hudecová D.2, Eybl V.3, Uher M.4
1 Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava
2 Department of Biochemistry and Microbiology, Faculty of Chemical and Food Technology STU, Bratislava, Slovak Republic
3 Department of Pharmacology and Toxicology, Charles University, Faculty of Medicine in Pilsen, Plzeň, Czech Republic
4 Department of Organic Chemistry, Faculty of Chemical and Food Technology STU, Bratislava, Slovak Republic

Kojic acid (5-hydroxy-2-hydroxymethyl-4-pyranone) represents an attractive polyfunctional skeleton for development of biologically active compounds. The authors prepared a great variety of kojic acid derivatives and selected biological properties have been studied. Thus, kojic acid derivatives are promising compounds that might advantageously be used in human and/or veterinary medicine and also in preparation of new, even more biologically active preparations.

Klíčová slova: kojic acid, 5-hydroxy-2-hydroxymethyl-4-pyranone, derivatives, chelating agent, fungicide, inhibitors of neoplastic cell growth

Zveřejněno: 1. březen 2004  Zobrazit citaci

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Brtko J, Rondahl L, Ficková M, Hudecová D, Eybl V, Uher M. Kojic Acid and its Derivatives: History and Present State of Art. Cent Eur J Public Health. 2004;12(Supplement):S16-18. PubMed PMID: 15141965.
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