Cent Eur J Public Health 2006, 14(1):22-24 | DOI: 10.21101/cejph.b0047

Serological Profile and Virological Evaluation of Hepatitis B and Hepatitis C Virus Infection among HIV Infected Patients in Greece

Ioannis S. Elefsiniotis1, Vassilios Paparizos2, Chrysoula Botsi2, Konstantinos D. Pantazis1, Andreas Katsambas2
1 Department of Internal Medicine, Hepatology Unit, Hippokration Hospital of Athens, Athens, Greece
2 University Clinic, Department of Infectious Diseases, "Andreas Sygros" Hospital, Athens, Greece

In this study we evaluate the prevalence of HBV and HCV infections and the HBV and/or HCV viral load as well as HCV genotype among 737 HIV-infected patients. 89/737 (12.1%) were HBsAg(+) and the majority of them (60.7%) were HBeAg(+), in contrast to general Greek population; anti-HBc seropositivity was detected in 48.1% of the study population. Serum HBV-DNA levels were 5.75±1.66 (-log10 copies/ml) and HBeAg(+) coinfected patients had significantly higher levels than HBeAg(-) ones (7.40±0.64 vs 4.59±1.01, respectively, p<0.001). 8.2% of HIV-infected patients were anti-HCV(+) and the majority of them (85.7%) had HCV-RNA levels more than 700.000 IU/l. The most common HCV-genotype was genotype-1 (12/28, 42.9%), representing a difficult-to-treat special population.

Keywords: hepatitis B virus, hepatitis C virus, HIV, coinfection

Received: August 11, 2005; Published: March 1, 2006  Show citation

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Elefsiniotis IS, Paparizos V, Botsi C, Pantazis KD, Katsambas A. Serological Profile and Virological Evaluation of Hepatitis B and Hepatitis C Virus Infection among HIV Infected Patients in Greece. Cent Eur J Public Health. 2006;14(1):22-24. doi: 10.21101/cejph.b0047. PubMed PMID: 16705877.
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