Cent Eur J Public Health 2006, 14(2):78-81 | DOI: 10.21101/cejph.b0045

Associaton of Insulin Resistance Linked Diseases and Hair Loss in Elderly Men. Finnish Population-based Study

Päivi Hirsso1, Mauri Laakso1,2, Veikko Matilainen1, Liisa Hiltunen1,2,3, Ulla Rajala1, Jari Jokelainen1,2, Sirkka Keinänen-Kiukaanniemi1,3
1 University of Oulu, Department of Public Health Science and General Practice, University of Oulu, Finland
2 Unit of General Practice, Oulu University Hospital, Finland
3 Oulu Health Center, City of Oulu, Finland

Previous investigations have shown an association of androgenetic alopecia (AGA) with insulin resistance related disorders such as ischemic heart disease. An association between AGA and anthropometric abnormalities linked with insulin resistance and heredity in women aged 63 years has also been shown. We therefore compared 63-year-old men with AGA and ones with normal hair status for insulin resistance linked parameters. A population of 245 men aged 63 years, who were participants in a population-based cross-sectional study in the City of Oulu, underwent a medical check-up including assessment of hair status on the Hamilton-Norwood scale and determination of anthropometric measures, blood pressure, fasting glucose and serum lipids.
Fifty eight per cent of the men reported extensive hair loss (grade III-VII). Hypertension and the use of antihypertensive drugs were common among men with AGA (61% vs. 45% and 50% vs. 26%, respectively). The rates of diabetes and hyperinsulinemia (21% vs. 12% and 61% vs. 49%) were higher among men with AGA compared to those with normal hair status but no difference was seen in other factors.
Our findings show that AGA is common among Finnish men aged 63 years but that it is also associated with insulin linked disturbances, such as hypertension and diabetes. Such men developing AGA might benefit from attention in medical check-up.

Keywords: androgenetic alopecia, hair loss, insulin resistance

Received: May 3, 2005; Revised: November 14, 2005; Accepted: November 14, 2005; Published: June 1, 2006  Show citation

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Hirsso P, Laakso M, Matilainen V, Hiltunen L, Rajala U, Jokelainen J, Keinänen-Kiukaanniemi S. Associaton of Insulin Resistance Linked Diseases and Hair Loss in Elderly Men. Finnish Population-based Study. Cent Eur J Public Health. 2006;14(2):78-81. doi: 10.21101/cejph.b0045. PubMed PMID: 16830609.
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    References

    1. Ford ES, Freedman DS, Byers T. Baldness and ischemic heart disease in a national sample of men. Am J Epidemiol. 1996 Apr 1;143(7):651-7. Go to original source...
    2. Hambly RI, Aintablian A, Hoffman I, Kramer J, Marx JW. Is male baldness a coronary risk factor? Clin Res. 1977;25(3):226A.
    3. Herrera CR, D'Agostino RB, Gerstman BB, Bosco LA, Belanger AJ. Baldness and coronary heart disease rates in men from the Framingham Study. Am J Epidemiol. 1995 Oct 15;142(8):828-33. Go to original source...
    4. Lesco S, Rosenberg L, Shapiro S. A case-control study of baldness in relation to myocardial infarction in men. JAMA. 1993 Feb 24;269(8):998- 1003. Erratum in: JAMA 1993 May 19;269(19):2508. Go to original source... Go to PubMed...
    5. Lotufo PA, Chae CU, Ajani UA, Hennekens CH, Manson JE. Male pattern baldness and coronary heart disease: the Physicians' Health Study. Arch Intern Med. 2000 Jan 24;160(2):165-71.
    6. Matilainen V, Koskela P, Keinanen-Kiukaanniemi S. Early androgenetic alopecia as a marker of insulin resistance. Lancet. 2000 Sep 30;356(9236):1165-6. Go to original source... Go to PubMed...
    7. Matilainen VA, Makinen PK, Keinanen-Kiukaanniemi SM. Early onset of androgenetic alopecia associated with early severe coronary heart disease: a population-based, case-control study. J Cardiovasc Risk. 2001 Jun;8(3):147-51. Go to original source...
    8. Matilainen V, Laakso M, Hirsso P, Koskela P, Rajala U, KeinanenKiukaanniemi S. Hair loss, insulin resistance, and heredity in middleaged women. A population-based study. J Cardiovasc Risk. 2003 Jun;10(3):227-31. Go to original source... Go to PubMed...
    9. Rajala U, Keinanen-Kiukaanniemi S, Uusimaki A, Reijula K, Kivela SL. Prevalence of diabetes mellitus and impaired glucose tolerance in a middle-aged Finnish population. Scand J Prim Health Care. 1995 Sep;13(3):222-8. Go to original source...
    10. Rajala U, Koskela P, Keinanen-Kiukaanniemi S. Hyperglycemia as a risk factor of mortality in a middle-aged Finnish population. J Clin Epidemiol. 2001 May;54(5):470-4. Go to original source...
    11. Norwood OT. Male pattern baldness: classification and incidence. South Med J. 1975 Nov;68(11):1359-65. Go to original source...
    12. World Health Organization. Diabetes mellitus: report of a WHO Study Group. Geneva: WHO; 1985. WHO Technical Report Series No. 727.
    13. Katz A, Nambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000 Jul;85(7):2402-10. Go to original source... Go to PubMed...
    14. Hrebíček J, Janout V, Malinčíková J, Horáková D, Čížek L. Detection of insulin resistance by simple quantitative insulin sensitivity check index QUICKI for epidemiological assessment and prevention. J Clin Endocrinol Metab. 2002 Jan;87(1):144-7. Go to original source...
    15. Ellis JA, Stebbing M, Harrap SB. Male pattern baldness is not associated with established cardiovascular risk factors in the general population. Clin Sci (Lond). 2001 Apr;100(4):401-4. Go to original source... Go to PubMed...
    16. Severi G, Sinclair R, Hopper JL, English DR, McCredie MR, Boyle P, et al. Androgenetic alopecia in men aged 40-69 years: prevalence and risk factors. Br J Dermatol. 2003 Dec;149(6):1207-13. Go to original source...
    17. Trevisan M, Farinaro E, Krogh V, Jossa F, Giumetti D, Fusco G, et al. Baldness and coronary heart disease risk factors. J Clin Epidemiol. 1993 Oct;46(10):1213-8. Go to original source...
    18. Tang PH, Chia HP, Cheong LL, Koh D. A community study of male androgenetic alopecia in Bishan, Singapore. Singapore Med J. 2000 May;41(5):202-5.
    19. Paik JH, Yoon JB, Sim WY, Kim BS, Kim NI. The prevalence and types of androgenetic alopecia in Korean men and women. Br J Dermatol. 2001 Jul;145(1):95-9. Go to original source...
    20. Kuster W, Happle R. The inheritance of common baldness: two B or not two B? J Am Acad Dermatol. 1984 Nov;11(5 Pt 1):921-6. Go to original source... Go to PubMed...
    21. TosiA, Misciali C, Piraccini BM, PelusoAM, Bardazzi F. Drug-induced hair loss and hair growth. Incidence, management and avoidance. Drug Saf. 1994 Apr;10(4):310-7. Go to original source... Go to PubMed...
    22. Whiting D, Howsden FL. Color atlas of differential diagnosis of hair loss. Fairfield: Canfield Publishing; 1998.

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