Cent Eur J Public Health 2006, 14(3):122-125 | DOI: 10.21101/cejph.a3387

Incidence of Orofacial Clefts in the Slovak Republic

Erika Macháčová1, Roman Bánsky2, Margita ©paleková1, ©tefan Guzanin3, Robert Sabovčík3, Ladislav Slobodník4
1 Institute of Epidemiology, Medical Faculty, Comenius University, Bratislava, Slovak Republic
2 Clinic of Plastic Surgery, Medical Faculty, Comenius University, Bratislava, Slovak Republic
3 Clinic of Plastic and Reconstructive Surgery, Medical Faculty, P.J.©afarik's University, Koąice, Slovak Republic
4 Department of Plastic, Estetic and Reconstructive Surgery, F.D. Roosvelt's Faculty Hospital, Banská Bystrica, Slovak Republic

Orofacial clefts (OC) are quite common congenital defects. Retrospective active survey collecting clinical data of children with OC examined and operated on in the three main specialized departments of plastic surgery in the Slovak Republic over 16 years (1985-2000) revealed total incidence of 1.61/103 live births (LB). 1,849 children suffering from OC were recognised out of 1,147,236 live births.
Total incidence (TI) of OC per 1,000 live births was determined by types, gender, regions, districts and seasonal variation. The highest rate, 40.5% of clefts, affected the primary and secondary palate (CLP), more than 32% were of cleft palate type (CP), about 26% cleft lip (CL) and about 1% of associated malformations (AM). Clefts in males (1.71 /103 LB) were significantly more common than in females (1.50/103 LB), sex ratio 1.14:1. Morbidity rates (TI) varies from 1.29/103 LB in the east Slovakia to the highest incidence of 1.93/103 LB in the middle Slovakia with wide range by district.
Comparing data from the study and from the national register, 17% of children with OC were missed. Presented survey assessed risk of OC in Slovakia at the rate 1 newborn with OC per 620 LB compared with notified frequency of 1 OC per 745 LB.

Keywords: incidence, orofacial clefts, live births, Slovakia

Received: February 20, 2006; Revised: April 25, 2006; Accepted: April 25, 2006; Published: September 1, 2006  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Macháčová E, Bánsky R, ©paleková M, Guzanin ©, Sabovčík R, Slobodník L. Incidence of Orofacial Clefts in the Slovak Republic. Cent Eur J Public Health. 2006;14(3):122-125. doi: 10.21101/cejph.a3387. PubMed PMID: 17152223.
Download citation

References

  1. Institute of Health Information and Statistics. Congenital Defects in SR 1985 - 2000. Bratislava: IHIS, Slovak Republic; 1986 - 2001. (In Slovak.)
  2. Tolarová M. Incidence of orofacial clefts in Bohemia from 1975 to 1982. Cesk Pediatr. 1986 Mar;41(3):131-5. (In Czech.)
  3. Kernahan DA, Stark RB. A new classification for cleft lip and palate. Plast Reconstr Surg. 1958 Nov;22(5):435-41. Go to original source...
  4. Taher AA. Cleft lip and palate in Tehran. Cleft Palate Craniofac J. 1992 Jan;29(1):15-6. Go to original source... Go to PubMed...
  5. Croen LA, Shaw GM, Wasserman CR, Tolarova MM. Racial and ethnic variations in the prevalence of orofacial clefts in California, 1983-1992. Am J Med Genet. 1998 Aug 27; 79(1):42-7. Go to original source...
  6. Kumar P, Hussain MT, Cardoso E, Hawary MB, Hassanain J. Facial clefts in Saudi Arabia: an epidemiologic analysis in 179 patients. Plast Reconstr Surg. 1991 Dec;88(6):955-8. Go to original source...
  7. Rajabian MH, Sherkat M. An epidemiologic study of oral clefts in Iran: analysisof1,669cases.CleftPalateCraniofacJ.2000Mar;37(2):191-6. Go to original source...
  8. Al Omari F,Al-Omari IK. Cleft lip and palate in Jordan: birth prevalence rate. Cleft Palate Craniofac J. 2004 Nov;41(6):609-12. Go to original source... Go to PubMed...
  9. Borkar AS, Mathur AK, Mahaluxmivala S. Epidemiology of facial clefts in the central province of Saudi Arabia. Br J Plast Surg. 1993 Dec;46(8):673-5. Go to original source... Go to PubMed...
  10. Derijcke A, Eerens A, Carels C. The incidence of oral clefts: a review. Br J Oral Maxillofac Surg. 1996 Dec;34(6):488-94. Go to original source...
  11. Antoszewski B, Kruk-Jeromin J. Epidemiology of cleft lip and palate in Lodz, Poland, in the years 1981-1995. Acta Chir Plast. 1997;39(4): 109-12. Go to PubMed...
  12. HagbergC,LarsonO,MileradJ.Incidenceofcleftlipandpalateandrisksof additionalmalformations.CleftPalateCraniofacJ.1998Jan;35(1):40-5.
  13. Peterka M, Peterkova R, Tvrdek M, Kuderova J, Likovsky Z. Significant differences in the incidence of orofacial clefts in fifty-two Czech districts between 1983 and 1997. Acta Chir Plast. 2000;42(4):124-9. Go to PubMed...
  14. Addor MC, Feldmeyer L, Hohlfeld J, Schorderet DF. Epidemiology of lip-maxilla-palate clefts in the canton of Vaud. Rev Med Suisse Romande. 2003 Aug;123(8):501-5. (In French.)
  15. Rosche C, Steinbicker V, Rose I. Incidence of facial clefts in the Magdeburg region. Mund Kiefer Gesichtschir 1998 Jan;2(1):5-10. (In German.) Go to original source... Go to PubMed...
  16. Kozelj V. Epidemiology of orofacial clefts in Slovenia, 1973-1993: comparison of the incidence in six European countries. J Craniomaxillofac Surg. 1996 Dec;24(26):378-82. Go to original source...
  17. Czeizel AE, Hirschberg J. Orofacial clefts in Hungary. Epidemiological and genetic data, primary prevention. Folia Phoniatr Logop. 1997;49(34):111-6. Go to original source... Go to PubMed...
  18. Bellis TH, Wohlgemuth B. The incidence of cleft lip and palate deformities in the south-east of Scotland (1971-1990). Br J Orthod. 1999 Jun;26(2):121-5. Go to original source... Go to PubMed...
  19. Gregg T, Boyd D, Richardson A. The incidence of cleft lip and palate in NothernIrelandfrom1980-1990.BrJOrthod.1994Nov;21(4):387-92. Go to original source...
  20. Macháčová E, ©paleková M, Brozman M, Hajdů E. An Epidemiological Study of Cleft Lip and Palate in Slovakia. Surg Childh Intern. 2000; 8:103-107.
  21. Macháčová E, Bánsky R, ©paleková M, Fedeleą J, Kroupová D. Orofacial clefts in western Slovakian regions. Epidemiol Mikrobiol Imunol. 2002;51(4):165-168. (In Slovak)
  22. Tolarova M. Orofacial clefts in Czechoslovakia. Incidence, genetics and prevention of cleft lip and palate over a 19-year-period. Scand J Plast Reconstr Surg Hand Surg. 1987;21(1):19-25. Go to original source...
  23. Černý M, Fára M, Hrivňáková J, Moucha L. Cleft lip and palate: Variability in the Czech population, sex ratio and familial incidence. Rozhl Chir. 1986 Oct;65(10):653-62. (In Czech.) Go to PubMed...
  24. Janovič J, Fedeleą J, Zboja ©. Current opinions on the complex treatment of cleft lip and palate. Lek Obz. 1997; 46:38-41. (In Slovak.)
  25. Cooper ME, Stone RA, LiuY, Hu DN, Melnick M, Marazita ML. Descriptive epidemiology of nonsyndromic cleft lip with or without cleft palate in Shanghai, China, from 1980 to 1989. Cleft Palate Craniofac J. 2000 May;37(3):274-80. Go to original source... Go to PubMed...
  26. Wang SL, Huang CS, Chen YR, Noordhoff MS. Cleft lip and cleft palate in the Craniofacial Center, Chang Gung Memorial Hospital: incidence, sex, seasonality and topographic distribution. ChanggengYi Xue Za Zhi. 1989 Dec 20;12(4):215-24. (In Chinese.)