Cent Eur J Public Health 2006, 14(3):130-132 | DOI: 10.21101/cejph.a3372

Preventive Administration of GS Imunostim as a Protection against Acute Respiratory Infections

Jiří Stanek1, Vladimír Príkazský2, Jozef Rosina1, Alexander M. Čelko1, Boris ©»astný3
1 Charles University in Prague, 3rd Medical Faculty, Prague, Czech Republic
2 National Institute of Public Health, Prague, Czech Republic
3 Canadian Medical Centre, Prague, Czech Republic

With respect to the fact that acute respiratory infections (hereafter ARI) are a world-wide serious social and economic problem, more and more attention is being paid to the development and application of oral bacterial immunomodulators.
The preventive effect of GS Imunostim has been evaluated during the respiratory season 2005. The study took place at 10 outpatient sites of general practitioners and lung specialists in Prague, Pilsen and Brno in the respiratory season from January to April 2005. The comparison with the ARI morbidity reports in the studied period revealed statistically significant morbidity reduction in the study participants compared to the ARI morbidity in the Czech population in the studied period from January to April 2005. The morbidity rate in the studied group was 7%, whereas ARI morbidity 15.1% was reported in the general population. The morbidity in the study group was significantly lower that in the general population.

Klíčová slova: GS Imunostim, prevention, bacterial lysates

Vloľeno: 15. listopad 2005; Revidováno: 18. duben 2006; Přijato: 18. duben 2006; Zveřejněno: 1. září 2006  Zobrazit citaci

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Stanek J, Príkazský V, Rosina J, Čelko AM, ©»astný B. Preventive Administration of GS Imunostim as a Protection against Acute Respiratory Infections. Cent Eur J Public Health. 2006;14(3):130-132. doi: 10.21101/cejph.a3372. PubMed PMID: 17152225.
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Reference

  1. Chlíbek R, Beran J, ©pliňo M. Effectiveness of influenza vaccination in healthy adults - a fourfold decrease in influenza morbidity during one influenza season. Epidemiol Mikrobiol Imunol. 2002 Apr;51(2):47-51. (In Czech.)
  2. Ensernik M. Epidemiology. Drugs, quarantine might stop a pandemic before it starts. Science. 2005 Aug 5;309(5736):870-1. Přejít k původnímu zdroji... Přejít na PubMed...
  3. Havlíčková M, Otavová M, Kynčl J. Surveillance of acute respiratory infections in the Czech Republic in the season 2004-2005. Zprávy CEM. 2005;14:286-93. (In Czech.)
  4. Bystroň J. Oral bacterial Immunomodulators and Evidence-Based Medicine. Alergie. 2003;5(4):284-290. (In Czech.)
  5. Present options of immunomodulatory therapy in practice. Farmakoterap inform. 2005;(1):1-2. (In Czech.)
  6. Tricarico D, VarricchioA, D'Ambrosio S,Ascione E, Motta G. Prevention of recurrent upper respiratory tract infections in a community of cloistered nuns using a new immunostimulating bacterial lysate. A randomized, double-blind clinical trial. Arzneimittelforschung. 2004;54(1):57-63. (In German.) Přejít k původnímu zdroji... Přejít na PubMed...
  7. Rossi S, Tazza R. Efficacy and safety of a new immunostimulating bacterial lysate in the prophylaxis of acute lower respiratory tract infections. A randomised, open, controlled clinical trial. Arzneimittelforschung. 2004;54(1):50-6. (In German.) Přejít k původnímu zdroji... Přejít na PubMed...
  8. Pozzi E, Serra C. Efficacy of Lantigen B in the prevention of bacterial respiratory infections. Monaldi Arch Chest Dis. 2004 Jan-Mar;61(1): 19-27. Přejít na PubMed...
  9. Volgin AR, Demina IuV. Experience of using bacterial lysate IRS 19 for the prophylaxis of the diseases of respiratory organs in organized groups. Zh Mikrobiol Epidemiol Immunobiol. 2005 May-Jun;(3):82-4. (In Russian.)
  10. Li J, Zheng JP, Yuan JP, Zeng GQ, Zhong NS, Lin CY. Protective effect of a bacterial extract against acute exacerbation in patients with chronic bronchitis accompanied by chronic obstructive pulmonary disease. Chin Med J. 2004 Jun;117(6):828-34.
  11. Ekberg-Jansson A, Larsson S, Lofdhal CG. Preventing exacerbations of chronic bronchitis and COPD. BMJ. 2001 May 26;322(7297):1259-61. Přejít k původnímu zdroji...
  12. Beran J, Moravík J. Effectiveness of vaccination against influenza in SkodaAuto Company employees during the influenza season 2000-2001. Cent Eur J Public Health. 2003;11(4):209-12.
  13. Verma BK, Thakur DK. Effect of stressful environmental factors upon neonatal immune system. Cent Eur J Public Health. 1995;3(1):25-9.
  14. Jedrychowski W, Kautery U, Flak E, Mroz E, Bianchi I. Cohort study on low physical activity level and recurrent acute respiratory infections in schoolchildren. Cent Eur J Public Health. 2001;9(3):126-9.
  15. Pinter A, Rudnai P, Sarkany E, Goczan M, Paldy A. Air pollution and childrens, respiratory morbidity in the Tata area, Hungary. Cent Eur J Public Health. 1996;4 Suppl:17-20.