Cent Eur J Public Health 2006, 14(3):138-140 | DOI: 10.21101/cejph.a3339

The Association between Copper Containing IUCD and Bacterial Vaginosis

ªayeste Demirezen1, Ayºegül Küçük1, M. Sinan Beksaç2
1 Hacettepe University, Faculty of Science, Department of Biology, 06532, Ankara, Turkey
2 Hacettepe University, Faculty of Medicine, Department of Gynecology and Obstetrics, Ankara, Turkey

This study was designed to investigate whether there is an association between bacterial vaginosis (BV) and the use of intrauterine contraceptive device (IUCD). Six hundred Papanicolaou stained cervicovaginal smears were analyzed cytologically. 56 of 600 patients (9.3%) were detected as having IUCD. Four of 56 (7,1%) and 10 of 544 (1.8%) were positive for BV [Bv (+)]. The duration of the use of IUCD was higher than 4 years in 3 of 4 patients who were BV (+). This study showed a significant correlation between the use of IUCD and the presence of BV statistically (p < 0.05). Our findings also suggest that time limited BV infection is associated with long term use of this device. It can be suggested that a periodic microscopic examination and use of IUCD (less than 5 years) are convenient to prevent this kind of anaerobic infection.

Keywords: bacterial vaginosis, intrauterine contraceptive device, cervicovaginal smears

Received: March 8, 2005; Revised: February 27, 2006; Accepted: February 27, 2006; Published: September 1, 2006  Show citation

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Demirezen ª, Küçük A, Beksaç MS. The Association between Copper Containing IUCD and Bacterial Vaginosis. Cent Eur J Public Health. 2006;14(3):138-140. doi: 10.21101/cejph.a3339. PubMed PMID: 17152227.
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    References

    1. Zipper JA, Tatum HJ, Pastene L, Medel M, Rivera M. Metallic copper as an intrauterine contraceptice adjunct to the "T" device. Am J Obstet Gynecol. 1969 Dec 15;105(8):1274-8. Go to original source...
    2. Nieves B. Bacterial vaginosis. Anaerobe. 1999 Jun;5(3-4):343-5. Go to original source...
    3. Hillier SL. Diagnostic microbiology of bacterial vaginosis. Am J Obstet Gynecol. 1993 Aug;169(2 Pt 2):455-9. Go to original source...
    4. CalzolariE,MasciangeloR,MiliteV,VerteramoR.Bacterialvaginosisand contraceptive methods. Int J Gynaecol Obstet. 2000 Sep;70(3):341-6. Go to original source...
    5. Shoubnikova M, Hellberg D, Nilsson S, Mardh PA. Contraceptive use in women with bacterial vaginosis. Contraception. 1997 Jun;55(6):355-8. Go to original source... Go to PubMed...
    6. Demirezen ª. Review of cytologic criteria of bacterial vaginosis: examination of 2,841 Papanicolaou-stained vaginal smears. Diagn Cytopathol. 2003 Sep;29(3):156-9. Go to original source... Go to PubMed...
    7. Smayevsky J, Canigia LF, Lanza A, Bianchini H. Vaginal microflora associated with bacterial vaginosis in nonpregnant women: reliability of sialidase detection. Infect Dis Obstet Gynecol. 2001;9(1):17-22. Go to original source... Go to PubMed...
    8. Tsanadis G, Kalantaridou SN, Kaponis A, Paraskevaidis E, Zikopoulos K, Gesouli E, et al. Bacteriological cultures of removed intrauterine devices and pelvic inflammatory disease. Contraception. 2002 May;65(5): 339-42. Go to original source... Go to PubMed...
    9. Goffinet F, Maillard F, Mihoubi N, Kayem G, Papiernik E, Cabrol D, et al. Bacterial vaginosis: prevalence and predictive value for premature delivery and neonatal infection in women with preterm labour and intact membranes. Eur J. Obstet Gynecol Reprod Biol. 2003 Jun 10;108(2): 146-51. Go to original source...
    10. Castro E, Dominguez M, Navarrete P, Boggiano G, Zemelman R. Prevalence of Bacterial vaginosis in women attending family planning clinics. Anaerobe. 1999 Jun;5(3-4):399-401. Go to original source...
    11. Ferraz do Lago R, Simoes JA, Bahamondes L, Camargo RP, Perrotti M, Monteiro I. Follow-up of users of intrauterine device with and without bacterial vaginosis and other cervicovaginal infections. Contraception. 2003 Aug;68(2):105-9. Go to original source... Go to PubMed...
    12. Platz-Christensen JJ, Larsson PG, Sundström E, Wiqvist N. Detection of bacterial vaginosis in wet mount, Papanicolaou stained vaginal smears and in gram stained smears. Acta Obstet Gynecol Scand. 1995 Jan;74(1):67-70. Go to original source... Go to PubMed...
    13. Elhag KM, Bahar AM, Mubarak AA. The effect of a copper intra-uterine contraceptive device on the microbial ecology of the female genital tract. J Med Microbiol. 1988 Apr;25(4):245-51. Go to original source... Go to PubMed...
    14. Wilson EM. The forgotten copper 7 - a circus tale. Brit J Fam Plann. 1999 Oct;25(3):122-3.
    15. Joesoef MR, Karundeng A, Runtupalit C, Moran JS, Lewis JS, Ryan CA. High rate of bacterial vaginosis among women with intrauterine devices in Monado, Indonesia. Contraception. 2001 Sep; 64(3):169-72. Go to original source... Go to PubMed...
    16. Çerikçioðlu N, Beksaç MS. Cytolitic vaginosis. Gynecol Obstet Reprod Med. 1997; 3(1):283-5.
    17. Demirezen S. Trichomonas vaginalis in vaginal smears of women using intrauterine contraceptive device. Cent Eur J Public Health. 2001 Nov;9(4):176-8.
    18. Kosonen A. Corrosion of copper in utero. Fertil Steril. 1978 Jul;30(1): 59-65. Go to original source... Go to PubMed...
    19. Merki-Feld GS, Lebeda E, Hogg B, Keller PJ. The incidence of actinomyces-like organisms in Papanicolaou-stained smears of copper- and levonorgestrel-releasing intrauterine devices. Contraception. 2000 Jun;61(6):365-8. Go to original source... Go to PubMed...
    20. Aggarwal AK, Kumar R, Gupta V, Sharma M. Community based study of reproductive tract infections among ever married women of reproductive age in a rural area of Haryana, India. J Commun Dis. 1999 Dec;31(4):223-8. Go to PubMed...
    21. Thomason JL, Gelbart SM, Anderson RJ, Walt AK, Osypowski PJ, Broekhuizen FF. Statistical evaluation of diagnostic criteria for bacterial vaginosis. Am J Obstet Gynecol. 1990 Jan;162(1):155-60. Go to original source...

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