Cent Eur J Public Health 2006, 14(4):186-188 | DOI: 10.21101/cejph.a1148

Blood Pressure Response to Exercise Test and Serum Lipids in Normotensive Men with Positive Family History of Hypertension

Christo Deyanov, Katia Vangelova
National Center of Public Health Protection, Sofia, Bulgaria

The aim of the study was to follow the arterial blood pressure response to exercise test and serum lipids in middle-aged normotensive men with family history (FH) of arterial hypertension. 152 normotensive men, divided into two groups: I group - 92 men without FH for arterial hypertension and II group - 60 men with family history for arterial hypertension were investigated. The response of blood pressure to exercise test on bicycle ergometer with progressively increasing workload up to 100 W was followed up. Five minute recovery period was followed, too. The total cholesterol (TC), high-density and low-density lipoprotein cholesterol (HDL-C and LDL-C) and triglycerides were assessed and TC/HDL-C ratio was calculated. Significant difference in the arterial blood pressure at a level of 100 W between the Ist and IInd group was found: 177±19.0/89±12.0 mmHg versus 189±17**/96±11* mmHg (* p < 0.01, ** p < 0.001). Subjects with positive FH for arterial hypertension showed higher elevation of arterial blood pressure during and after exercise: OR = 2.3 (95% CI 1.1 - 4.8). The systolic blood pressure during the recovery period and TC/HDL-C ratio were significantly higher with the IInd group. In conclusion, our data show significantly higher reaction of blood pressure to exercise, retarded recovery of blood pressure and significantly higher TC/HDL-C ratio with the individuals with positive FH for arterial hypertension.

Keywords: hypertension, family history, exercise test, blood pressure response, serum lipids

Received: August 12, 2005; Revised: July 11, 2006; Accepted: July 11, 2006; Published: December 1, 2006  Show citation

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Deyanov C, Vangelova K. Blood Pressure Response to Exercise Test and Serum Lipids in Normotensive Men with Positive Family History of Hypertension. Cent Eur J Public Health. 2006;14(4):186-188. doi: 10.21101/cejph.a1148. PubMed PMID: 17243498.
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    References

    1. Deyanov C. Risk assessment and prognosis of the arterial hypertension depending from the haemodynamic response during exercise stress test. Savr Med. 1995;46(1):3-6. (In Bulgarian.)
    2. Franz IW. ABPM and ergometry for evaluation of hypertension. NierenHochdruckkr. 1995;24(3):90-2. (In German.)
    3. Singh JP, Larson MG, Manolio TA, O'Donnell CJ, Lauer M, Evans JC, et al. Blood pressure response during treadmill testing as a risk factor for new-onset hypertension. Circ. 1999;99(14):1831-6. Go to original source... Go to PubMed...
    4. Miyaai N, Arita M, Miyashita K, Morioka I, Shiraishi T, Nishio I. Blood pressure response to heart rate during exercise test and risk of future hypertension. Hypertension. 2002;39(3):761-79. Go to original source... Go to PubMed...
    5. Bond VJ, Don Franks B, Tearney RJ, Wood B, Melendez MA, Johnson L, et al. Exercise blood pressure response and skeletal muscle vasodilator capacity in normotensives with positive and negative family history of hypertension. J Hypertens. 1994;12(3)285-90. Go to original source...
    6. Falkner B, Onesti G, Hamstra B. Stress response characteristics of adolescents with high genetic risk for essential hypertension: a five-year follow-up. Clin Exp Hypertens. 1981;3(4):583-91. Go to original source... Go to PubMed...
    7. Rodigues BM, Penneni JJ. Cardiovascular hyperactivity in patients with family history of high blood pressure. Med Clin (Barc). 2004;123(19):72630. (In Spanish.)
    8. Gosse P, Durandet P, Roudaut R, Broustet JP, Dallocchio M. Prognostic value of arterial pressure during exertion in hypertensive subjects. Arch Mal Coeur Vaiss. 1989;82(7):1339-42. (In French.) Go to PubMed...
    9. Kato K, Saito F, Hatamo K, Noda S. Prognostic value of abnormal postexercise systolic BP response. Am Heart J. 1990;119(2):264-71. Go to original source...
    10. Mallion JM, Baquet JP, Tremel F, Siche JP, De Gaudemaris R. Diagnostic and prognostic value of exercise testing. J Cardiovasc Pharmacol. 1995; 25 Suppl 1:S15-9. Go to original source...
    11. Laukkanen JA, Kurl S, LakkaTA, Rauramaa R, Salonen JT. Systolic blood pressure during recovery from exercise and the risk of acute myocardial infarction in middle-aged men. Hypertension. 2004;44(6):820-7. Go to original source... Go to PubMed...
    12. Deyanov C, Vangelova K. Ambulatory blood pressure holter monitoring and plasma lipid profile in normotensive and hypertesive men.Ann Scient Papers, IMAB. 1999;5(1):113-4.
    13. Torbova S, Baurenski L, Biatcheva V, Kerekovska M. Serum lipids and risk factors for coronary heart disease. Actual Lipidology. 1997;2:3-9.
    14. The sixth report of the Joint National Committee on prevention, detec tion, evaluation, and treatment of high blood pressure. Arch Intern Med. 1997;157(21):2413-46.
    15. Jokiniitty J, Majahalme S, Kahonen M, Tuomisto MT, Turjanmaa V. Can blood pressure responses to tests unmask future blood pressure trends and the need for antihypertensive medication? Ten year of follow-up. Clin Physiol Funct Imaging. 2002;22(2):125-33. Go to original source...

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