Cent Eur J Public Health 2007, 15(3):103-105 | DOI: 10.21101/cejph.a3437

Obesity and Insulin Resistance in Childhood

Dalibor Pastucha1, Jana Malinčíková1, Jiří Hyjánek2, Dagmar Horáková3, Luděk Čížek3, Gabriela Janoutová3, Vladimír Janout3
1 Clinic for Rehabilitation and Movement Medicine, Faculty of Medicine, Palacky University, Olomouc, Czech Republic
2 Department for Medical Genetics and Fetal Medicine, Faculty of Medicine, Palacky University, Olomouc, Czech Republic
3 Department of Preventive Medicine, Faculty of Medicine, Palacky University, Olomouc, Czech Republic

Obesity is a serious risk factor for insulin resistance leading to diabetes and other disorders. As it is also occurring at ever younger age groups the aim of this study was to compare average levels of the homeostatic indices HOMA and QUICKI in obese compared to healthy children in an effort to find convenient markers for insulin sensitivity in clinical pediatric practice. Twenty one obese and 29 healthy children were selected. The average level of HOMA in obese children was 3,6, in healthy children 1,7 while the average level of QUICKI in obese children was 0,33 and in healthy children 0,36. The results demonstrate the possibility of insulin sensitivity assessment using these indices in pediatric practice. QUICKI has a narrower confidence interval and thus lower variability.

Keywords: obesity in children, insulin resistance, HOMA, QUICKI

Received: June 6, 2007; Revised: June 11, 2007; Accepted: June 11, 2007; Published: September 1, 2007  Show citation

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Pastucha D, Malinčíková J, Hyjánek J, Horáková D, Čížek L, Janoutová G, Janout V. Obesity and Insulin Resistance in Childhood. Cent Eur J Public Health. 2007;15(3):103-105. doi: 10.21101/cejph.a3437. PubMed PMID: 17958201.
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