Cent Eur J Public Health 2008, 16(1):17-20 | DOI: 10.21101/cejph.a3442
Fruit and Vegetable Intake and the Risk for Developing Coronary Heart Disease
- Faculty of Medicine, University of Ni¹, Serbia
The aim of the paper was to study the relationship between dietary intake of fruit and vegetable intake and the risk of coronary heart disease. We used data from a case-control study, conducted from 2001 to 2003, among 290 randomly selected cases (mean age 59.98 ± 10.03 years) with first event of an acute coronary syndrome and 290 selected paired controls by sex, age and region (mean age 59.43 ± 10.10 years), admitted to the same hospitals as cases without any suspicion of coronary disease. Using questionnaires, we assessed fruit and vegetable intake and estimated odds ratio of developing coronary heart disease by the intake. The benefit of fruit or vegetable consumption increased proportionally by the number of servings consumed (p for trend < 0.0001). Those in the upper tertile of fruit consumption (≥ 5 items/day) had 60% lower risk for coronary heart disease (odds ratio = 0.56, 95% CI = 0.35-0.89, p < 0.05), when compared to those in the lowest tertile (<1 item/day). Consumption of vegetable ≥3 items/day was associated with 70% lower risk of coronary heart disease (OR = 0.25, 95% CI = 0.09 - 0.66, p < 0.05), compared to subjects who did not consume vegetables. In agreement with previous studies, we found an inverse relation between vegetable and fruit intake and coronary heart risk. Consumption of fruits and vegetables seemed to provide significant protection against coronary heart disease.
Keywords: fruit intake, vegetable intake, diet, risk, coronary heart disease
Received: August 6, 2007; Revised: October 29, 2007; Accepted: October 29, 2007; Published: March 1, 2008 Show citation
References
- Reddy KS, Yusuf S. Emerging epidemic of cardiovascular disease in developing countries. Circulation. 1998 Feb 17;97(6):596-601.
Go to original source...
- World Health Organisation. Diet, nutrition and the prevention of chronic diseases. Technical report Series 916. Geneva: WHO; 2003.
- Bonow RO, Eckel RH. Diet, obesity, and cardiovascular risk. N Engl J Med. 2003 May 22;348(21):2057-8.
Go to original source...
Go to PubMed...
- Din R. Diet and cardiovascular disease. Am J Public Health. 2002 Jul;92(7):1050-1.
Go to original source...
- Hu FB,WillettWC. Optimal diets for prevention of coronary heart disease. JAMA. 2002 Nov 27;288(20):2569-78.
Go to original source...
- Roberts CK, Barnard RJ. Effects of exercise and diet on chronic disease. J Appl Physiol. 2005 Jan;98(1);3-30.
Go to original source...
Go to PubMed...
- World Health Organisation. The World health report 2002: reducing risks promoting healthy life. Geneva: WHO; 2002.
- Krauss RM, Eckel RH, Howard B,Appel LJ, Daniels SR, Deckelbaum RJ, et al. AHA Dietary Guidelines, revision 2000: a statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation. 2000 Oct 31;102(18):2284-99.
Go to original source...
- Kromhout D. 'Protective nutrients'and up-to-date dietary recommendations. Eur Heart J. 2001;Suppl 3:D33-6.
Go to original source...
- De Waart FG, Schouten EG, StalenhoefAFH, Kok FJ. Serum carotenoids, {alpha}-tocopherol and mortality risk in a prospective study among Dutch elderly. Int J Epidemiol. 2001 Feb;30(1):136-43.
Go to original source...
- Genkinger JM, Platz EA, Hoffman SC, Comstock GW, Helzlsouer KJ. Fruit, vegetable, and antioxidant intake and all-cause, cancer, and cardiovascular disease mortality in a community-dwelling population in Washington County, Maryland. Am J Epidemiol. 2004 Dec 15;160(12):1223-33.
Go to original source...
- Knekt P, Jarvinen R, Reunanen A, Maatela J. Flavonoid intake and coronary mortality in Finland: a cohort study. BMJ. 1996 Feb 24;312(7029):478-81.
Go to original source...
Go to PubMed...
- Padayatty SJ, Katz A, Wang Y, Eck P, Kwon O, Lee JH, et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22(1):18-35.
Go to original source...
Go to PubMed...
- Osganian SK, Stampfer MJ, Rimm E, Spiegelman D, Manson JE, Willett WC. Dietary carotenoids and risk of coronary artery disease in women. Am J Clin Nutr. 2003 Jun; 77(6):1390-9.
Go to original source...
Go to PubMed...
- Wannamethee SG, Lowe GD, RumleyA, Bruckdorfer KR, Whincup PH. Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis. Am J Clin Nutr. 2006 Mar;83(3):56774.
Go to original source...
Go to PubMed...
- Steffen LM, Jacobs DR Jr, Stevens J, Shahar E, Carithers T, Folsom AR. Associations of whole-grain, refined-grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study. Am J Clin Nutr. 2003 Sep;78(3):383-90.
Go to original source...
Go to PubMed...
- Dauchet L,Amouyel P, Dallongeville J. Fruit and vegetable consumption and risk of stroke: a meta-analysis of cohort studies. Neurology. 2005 Oct 25;65(8):1193-7.
Go to original source...
Go to PubMed...
- Liu S, Lee IM, Ajani U, Cole SR, Buring JE, Manson JE. Intake of vegetables rich in carotenoids and risk of coronary heart disease in men: The Physicians' Health Study. Int J Epidemiol. 2001 Feb;30(1):130-5.
Go to original source...
- Samman S, Sivarajah G, Man JC, Ahmad ZI, Petocz P, Caterson ID. A mixed fruit and vegetable concentrate increases plasma antioxidant vitamins and folate and lowers plasma homocysteine in men. J Nutr. 2003 Jul;133(7):2188-93.
Go to original source...
Go to PubMed...
- Steptoe A, Perkins-Porras L, McKay C, Rink E, Hilton S, Cappuccio FP. Behavioural counselling to increase consumption of fruit and vegetables in low income adults: randomised trial. BMJ. 2003 Apr 19;326(7394):855.
Go to original source...
Go to PubMed...
- Deljanin Z, Ranciæ N, Iliæ M, Petroviæ B, Tiodoroviæ B.Acute myocardial infarction morbidity and mortality in population of 30-64 years of age in the city of Nis in the period from 2001 to 2005. Acta Med Medianae. 2007;46(2):21-4.
- Gaziano JM, Manson JE, Branch LG, Colditz GA, Willett WC, Buring JE. A prospective study of consumption of carotenoids in fruits and vegetables and decreased cardiovascular mortality in the elderly. Ann Epidemiol. 1995 Jul;5(4):255-60.
Go to original source...
Go to PubMed...
- Hung HC, Joshipura KJ, Jiang R, Hu FB, Hunter D, Smith-Warner SA, et al. Fruit and vegetable intake and risk of major chronic disease. J Natl Cancer Inst. 2004 Nov 3; 96(21):1577-84.
Go to original source...
Go to PubMed...
- Ness AR, Powles JW. Fruit and vegetables, and cardiovascular disease: a review. Int J Epidemiol. 1997 Feb;26(1):1-13.
Go to original source...
- Joshipura KJ, Hu FB, Manson JE. Stampfer MJ, Rimm EB, Speizer FE, et al. The effect of fruit and vegetable intake on risk for coronary heart disease. Ann Intern Med. 2001 Jun 19;134(12):1106-14.
Go to original source...
- Van't Veer P, Jansen MC, Klerk M, Kok FJ. Fruit and vegetables in the prevention of cancer and cardiovascular disease. Public Health Nutr. 2000 Mar;3(1):103-7.
Go to original source...
Go to PubMed...
- Nikoliæ M, Mitroviæ V, Lukiæ N, Lazareviæ K. Diet as a risk factor of cancer among the population of Ni¹. Arch Oncol. 2006;14(3-4):115-7.
Go to original source...
- Mozaffarian D, Kumanyika SK, Lemaitre RN, Olson JL, Burke GL, Siscovick DS. Cereal, fruit, and vegetable fiber intake and the risk of cardiovascular disease in elderly individuals. JAMA. 2003 Apr 2;289(13):1659-66.
Go to original source...
Go to PubMed...
- Martínez-Ortiz JA, Fung TT, Baylin A, Hu FB, Campos H. Dietary patterns and risk of nonfatal acute myocardial infarction in Costa Rican adults. Eur J Clin Nutr. 2006 Jun;60(6):770-7.
Go to original source...
Go to PubMed...