Cent Eur J Public Health 2008, 16(4):205-208 | DOI: 10.21101/cejph.a3459
The Effect of Microelements Supplementation on β-oxidation Activity in Healthy and Type 1 Diabetic Rats
- 1 Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Poland
- 2 Pedagogical Faculty, Hradec Králové University, Hradec Králové, Czech Republic
Diabetes mellitus type 1 disease changes the activity of fatty acid degradation as compared to healthy animals. Supplementation in vitro with microelements chromium Cr3+ and selenium Se4+ and Se2- in non-toxic ([96.15 μmol (5 ppm) for chromium and 6.33 μmol (0.5 ppm) for selenium] concentrations strongly stimulates the activity of this process in diabetic rats. In healthy animals only chromium Cr3+ in concentration of 96.15 μmol (5 ppm) stimulated β-oxidation activity in lymphocytes. It may indicate the beneficial effect of supplementation of the diet with microelements, chromium Cr3+ and selenium Se4+ or Se2- at concentrations as low as 100 μmol for chromium and 6 μmol for selenium, respectively.
Klíčová slova: microelements, type 1 diabetes mellitus, rats, β-oxidation
Vloženo: 26. listopad 2007; Revidováno: 28. leden 2008; Přijato: 28. leden 2008; Zveřejněno: 1. prosinec 2008 Zobrazit citaci
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