Cent Eur J Public Health 2015, 23(2):170-175 | DOI: 10.21101/cejph.a4040
Evaluation of Cat Scratch Disease Cases Reported from Turkey between 1996 and 2013 and Review of the Literature
- Department of Infectious Diseases and Clinic Microbiology, Private Ümit Hospital, Eskişehir, Turkey
Background: Cat scratch disease (CSD), the most common cause of chronic lymphadenopathy among children and adolescents, typically features regional lymphadenitis associated with inoculation site due to a cat scratch or bite.
Objective: The aim of this study was to systematically review the articles related to CSD which were reported from Turkey in national and international journals in the last 18 years with a pooled-analysis method.
Methods: The articles related to CSD were retrieved by search of four national (Ulakbim Turkish Medical Literature Databases) and three international databases (Pub-Med, Science Citation Index (SCI) and Google scholar).
Results: Between the years 1996-2013, CSD cases have been published in a total of 16 articles (4 international, 12 national). These articles which were presented as a case report included a total of 18 CSD cases (38.8% women, 61.2% men; median age 16 years). The most common clinicopathologic subtypes of CSD are regional lymphadenitis (n=9), hepatosplenic (n=3) and neuroretinitis (n=2). The most common complaints of patients were swelling (94.4%), fever (61.2%) and weakness (50%) at admission. On exam, the most common signs were lymphadenopathy (94.4%), fever (61.2%), splenomegaly (16.6%), and skin eruption (16.6%).
Conclusion: This pooled analysis which enabled the evaluation of a large number of CSD cases, indicated that careful evaluation of clinical findings and histopathological investigation will provide valuable support for diagnosis and treatment of CSD.
Keywords: cat scratch disease, lymphadenitis, Turkey
Received: May 7, 2014; Revised: March 18, 2015; Accepted: March 18, 2015; Published: June 1, 2015 Show citation
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