Cent Eur J Public Health 2016, 24(4):268-271

Relative Importance of Traditional Risk Factors for Malignant Melanoma in the Czech Population

Lucie Rajská1,2, Dana Göpfertová2, Jana Hercogová1, Anna Jiráková1, Zuzana Sečníková1,2, Filip Rob1, Zdeněk ©merhovský2
1 Department of Dermatology and Venereology, 2nd Faculty of Medicine, Charles University and Bulovka Hospital, Prague, Czech Republic
2 Department of Epidemiology, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic

Aim: The Czech Republic is one of the leading European countries in incident cases of malignant melanoma (MM), which is on the rise. The study objective was to assess the strength of associations between MM and the known generally accepted risk factors for MM in the population of the Czech Republic.

Methods: The study was designed as a case-control study where cases were incident cases of MM detected at the Department of Dermatology and Venereology of the Bulovka Hospital. Controls were selected from cancer-free patients admitted to departments other than Dermatology and Venereology. Validated questionnaires were used to collect demographic, epidemiological, and clinical data.

Results: The binary logistic model shows the main risk factors for MM: male, female (OR=0.292, 95% CI=0.175-0.486), a changed mole (OR=6.371, 95% CI=3.774-10.756), a history of skin cancer (OR=95.704, 95% CI=37.241-10.756), and sunbeds use (OR=3.594, 95% CI=1.288-10.028). Using sunscreen products was considered as a protective factor against MM (OR=0.253, 95% CI=0.137-0.466).

Conclusion: The primary and secondary prevention increasingly emerges as a public health priority in the effort to reverse the negative trend in cases of MM and mortality from this disease in the Czech Republic. A prerequisite for an effective secondary prevention through screening is, among others, the identification of the population groups at highest risk for MM.

Keywords: incidence, malignant melanoma, risk factors, screening, questionnaire, case-control study

Received: September 20, 2015; Revised: November 11, 2015; Accepted: November 11, 2015; Published: December 1, 2016  Show citation

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Rajská L, Göpfertová D, Hercogová J, Jiráková A, Sečníková Z, Rob F, ©merhovský Z. Relative Importance of Traditional Risk Factors for Malignant Melanoma in the Czech Population. Cent Eur J Public Health. 2016;24(4):268-271. PubMed PMID: 28095280.
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