Cent Eur J Public Health 2018, 26(2):87-91 | DOI: 10.21101/cejph.a4764

Mortality rate of ICU patients with the Middle East Respiratory Syndrome - Coronavirus infection at King Fahad Hospital, Jeddah, Saudi Arabia

Mohammed A. Garout1, Hani A.A. Jokhdar1, Imad A. Aljahdali1, Ahmed R. Zein2, Reda A. Goweda1,3, Abdurahman Hassan-Hussein1
1 Department of Community Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia
2 Intensive Care Department, King Fahad Hospital, Jeddah, Kingdom of Saudi Arabia
3 Department of Family Medicine, Faculty of Medicine, Suez Canal University, Egypt

Objective: The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a novel coronavirus circulating in the Arabian Peninsula since September 2012. It leads to significant respiratory disease and among patients with co-morbidities is associated with high mortality. This research studied the mortality rate of MERS-CoV among intensive care unit (ICU) patients and the correlation of mortality with different co-morbidities.

Methods: This was a retrospective observational study conducted at the Intensive Care Unit of the King Fahad Hospital, Jeddah, Saudi Arabia. Data was obtained through patient chart review.

Results: The total sample consisted of 52 laboratory-confirmed MERS-CoV infection patients. 39 patients died, with a 75% case-fatality rate. Many patients had underlying co-morbidities, including diabetes mellitus (51.9%), hypertension (46.2%), and chronic renal disease (21.2%).

Conclusions: MERS-CoV ICU mortality remains markedly high due to a combination of factors; the disease process of MERS-CoV leads to multiple organ failure, particularly respiratory and renal failure.

Keywords: Middle East Respiratory Syndrome Coronavirus, mortality, intensive care units, Saudi Arabia

Received: March 9, 2016; Revised: November 25, 2017; Accepted: November 25, 2017; Published: June 30, 2018  Show citation

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Garout MA, Jokhdar HAA, Aljahdali IA, Zein AR, Goweda RA, Hassan-Hussein A. Mortality rate of ICU patients with the Middle East Respiratory Syndrome - Coronavirus infection at King Fahad Hospital, Jeddah, Saudi Arabia. Cent Eur J Public Health. 2018;26(2):87-91. doi: 10.21101/cejph.a4764. PubMed PMID: 30102495.
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