Cent Eur J Public Health 2019, 27(2):110-114 | DOI: 10.21101/cejph.a5524

Lead contamination of fruit spirits intended for own consumption as a potential overlooked public health issue? A pilot study

Mária Tatarková1, Tibor Baška1, Miroslava Sovičová1, Stanislav Kuka1, Eliška Štefanová1, Martin Novák1, Barbora Váňová2, Henrieta Hudečková1
1 Department of Public Health, Jessenius Faculty of Medicine in Martin, Comenius University, Martin, Slovak Republic
2 Department of Molecular Biology, Jessenius Faculty of Medicine in Martin, Comenius University, Martin, Slovak Republic

Objective: The aim of the study was to analyse the occurrence of lead in selected samples of fruit distilled spirits for own consumptions in terms of possible contribution to the occurrence of alcohol-attributable diseases.

Methods: In a pilot study, we analysed 18 samples of fruit spirits for own consumption. Most of the samples were distilled in the local growing distilleries in the Žilina Region with exception of 3 samples collected in the Trnava Region (one of them was of Hungarian origin). Sample preparation included previous mineralization with use of microwave decomposition system Multiwave 60 50 Hz. The samples were analysed by atomic absorption spectroscopy with graphic furnace (AAS GBC XplorAA 5000 with GF 5000).

Results: The average ethanol level in our samples was higher in comparison with distributed spirits. We detected lead in all samples. In two of them the concentration was lower than the limit of quantitation (LOQ). The highest lead concentrations were observed in plum spirit from Hungary (581.0 μg/l), and in grape spirit made in the Trnava Region (466.3 μg/l).

Conclusions: Lead is a widespread contaminant of fruit spirits prepared for own consumption. Taking into consideration its common occurrence and possible multiplicative effect with ethanol, we can assume that lead can contribute to the occurrence of several alcohol-attributable chronic diseases. Due to the insufficient information in this field, our results provide significant insight into the issue and present an important starting point for further research.

Keywords: lead, fruit spirits, analysis

Received: September 4, 2018; Revised: April 24, 2019; Accepted: April 24, 2019; Published: June 26, 2019  Show citation

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Tatarková M, Baška T, Sovičová M, Kuka S, Štefanová E, Novák M, et al.. Lead contamination of fruit spirits intended for own consumption as a potential overlooked public health issue? A pilot study. Cent Eur J Public Health. 2019;27(2):110-114. doi: 10.21101/cejph.a5524. PubMed PMID: 31241285.
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References

  1. Wani AL, Ara A, Usmani JA. Lead toxicity: a review. Interdiscip Toxicol. 2015 Jun;8(2):55-64. Go to original source... Go to PubMed...
  2. Rehm J, Kailasapillai S, Larsen E, Rehm MX, Samokhvalov AV, Shield KD, et al. A systematic review of the epidemiology of unrecorded alcohol consumption and the chemical composition of unrecorded alcohol. Addiction. 2014 Jun;109(6):880-93. Go to original source... Go to PubMed...
  3. Lachenmeier DW, Ganss S, Rychlak B, Rehm J, Sulkowska U, Skiba M, et al. Association between quality of cheap and unrecorded alcohol products and public health consequences in Poland. Alcohol Clin Exp Res. 2009 Oct;33(10):1757-69. Go to original source... Go to PubMed...
  4. Lachenmeier DW, Samokhvalov AV, Leitz J, Schoeberl K, Kuballa T, Linskiy IV, et al. The composition of unrecorded alcohol from eastern Ukraine: is there a toxicological concern beyond ethanol alone? Food Chem Toxicol. 2010 Oct;48(10):2842-7. Go to original source... Go to PubMed...
  5. Lachenmeier DW, Monakhova YB, Rehm J. Influence of unrecorded alcohol consumption on liver cirrhosis mortality. World J Gastroenterol. 2014 Jun 21;20(23):7217-22. Go to original source... Go to PubMed...
  6. Gupta V, Gill KD. Influence of ethanol on lead distribution and biochemical changes in rats exposed to lead. Alcohol. 2000 Jan;20(1):9-17. Go to original source... Go to PubMed...
  7. Flora SJ, Tandon SK. Effect of combined exposure to lead and ethanol on some biochemical indices in the rat. Biochem Pharmacol. 1987 Feb 15;36(4):537-41. Go to original source... Go to PubMed...
  8. Flora SJ, Gautam P, Kushwaha P. Lead and ethanol co-exposure lead to blood oxidative stress and subsequent neuronal apoptosis in rats. Alcohol Alcohol. 2012 Mar-Apr;47(2):92-101. Go to original source... Go to PubMed...
  9. Jurczuk M, Moniuszko-Jakoniuk J, Brzóska MM. Involvement of some low-molecular thiols in the peroxidative mechanisms of lead and ethanol action on rat liver and kidney. Toxicology. 2006 Feb 15;219(1-3):11-21. Go to original source... Go to PubMed...
  10. Caldas NM, Oliveira SR, Neto JA. Feasibility of internal standardization in the direct and simultaneous determination of As, Cu and Pb in sugarcane spirits by graphite furnace atomic absorption spectrometry. Anal Chim Acta. 2009 Mar 16;636(1):1-5. Go to original source... Go to PubMed...
  11. Vilar M, Barciela J, García-Martín S, Peña RM, Herrero C. Comparison of different permanent chemical modifiers for lead determination in Orujo spirits by electrothermal atomic absorption spectrometry. Talanta. 2007 Mar 15;71(4):1629-36. Go to original source... Go to PubMed...
  12. Jurado JM, Martín MJ. Pablos F, Moreda-Piñeiro A, Bermejo-Barrera P. Direct determination of copper, lead and cadmium in aniseed spirits by electrothermal atomic absorption spectrometry. Food Chem. 2007;101(3):1296-304. Go to original source...
  13. Rusu TE, Socaciu C, Părău C, Mocan AA. Quality and safety analysis for some traditional homemade fruit distillates from Transylvania (North West Romania). Bull Univ Agric Sci Vet Med Cluj-Napoca Agric. 2010;67(2):395-403. Go to original source...
  14. Gogoasa I, Rivis A, Velciov A, Gergen I. Heavy metals as potential contaminants of different assortments of fruit brandy in the Banat Area. J Horticult Forestry Biotechnol. 2013;17(3):134-6.
  15. Bonić M, Tešević V, Nikićević N, Cvejić J, Milosavljević S, Vajs V, et al. The contents of heavy metals in Serbian old plum brandies. J Serbian Chem Soc. 2013;78(7):933-45. Go to original source...
  16. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Alcohol consumption and ethyl carbamate. IARC Monogr Eval Carcinog Risks Hum. 2010;96:3-1383.
  17. Lachenmeier DW, Przybylski MC, Rehm J. Comparative risk assessment of carcinogens in alcoholic beverages using the margin of exposure approach. Int J Cancer. 2012 Sep 15;131(6):E995-1003. Go to original source... Go to PubMed...
  18. Ibanez JG, Carreon-Alvarez A, Barcena-Soto M, Casillas N. Metals in alcoholic beverages: A review of sources, effects, concentrations, removal, speciation, and analysis. J Food Compost Anal. 2008 Dec;21(8):672-83. Go to original source...
  19. World Health Organization. Global status report on alcohol and health 2014. Geneva: WHO; 2014.