Cent Eur J Public Health 2020, 28(1):70-73 | DOI: 10.21101/cejph.a5346

Seroprevalence of hepatitis E among hospitalized patients in Slovakia: first report

Zuzana Paraličová1, Monika Halánová2, Ivan Schréter1, Zuzana Kalinová2, Martin Novotný1, Jakub Sekula1, Ján Paralič3, Pavol Kristian1
1Department of Infectology, Travel Medicine, Faculty of Medicine, Pavol Jozef Šafárik University, Louis Pasteur University Hospital, Košice, Slovak Republic
2Department of Epidemiology, Faculty of Medicine, Pavol Jozef Šafárik University, Košice, Slovak Republic
3Department of Cybernetics, Artificial Intelligence, Faculty of Electrical Engineering, Informatics, Technical University of Košice, Košice, Slovak Republic

Objective: Hepatitis E infection is one of the most frequent acute hepatitis in the world. Currently five human genotypes with different geographical distributions and distinct epidemiologic patterns are identified. In Slovakia, only rare cases of hepatitis E have been reported in recent years. Therefore, the aim of the study was to evaluate the prevalence of anti-HEV total antibodies and the main risk factors for HEV in the general population in Eastern Slovakia.

Methods: Detection of anti-HEV total antibodies samples was done by a commercial enzyme-linked immunosorbent assay (ELISA) kit.

Results: Of 175 hospitalized patients included in the study, 76 (43.5%) showed positivity for anti-HEV total antibodies. No statistically significant differences were found in anti-HEV positivity between men and women or in the groups of different living areas (town/village - urban/rural).

Conclusion: Prevalence of anti-HEV total antibodies of hospitalised patients was high. The risk factor significantly associated with antibody positivity was eating raw meat. Other factors, such as sex, age, living area and contact with animals were not associated with antibody positivity.

Keywords: hepatitis E, seroprevalence, hospitalized patients, Slovakia

Received: March 15, 2018; Revised: December 16, 2019; Accepted: December 16, 2019; Published: March 30, 2020  Show citation

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Paraličová Z, Halánová M, Schréter I, Kalinová Z, Novotný M, Sekula J, et al.. Seroprevalence of hepatitis E among hospitalized patients in Slovakia: first report. Cent Eur J Public Health. 2020;28(1):70-73. doi: 10.21101/cejph.a5346. PubMed PMID: 32228821.
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