Cent Eur J Public Health 2021, 29(1):23-27 | DOI: 10.21101/cejph.a6143

Coexistence of asthmatic and non-respiratory allergic symptoms in children of Batumi Region, Georgia: occurrence and association with known diagnosis of asthma

Vakhtang Beridze1, Tamar Bakhtadze1, Sophio Beridze1, Karaman Phagava2, Ivane Chkhaidze3, Grzegorz Marek Brożek4, Jan Eugeniusz Zejda4
1 M. Iashvili Batumi Maternity and Child Central Hospital, Shota Rustaveli State University, Batumi, Georgia
2 Department of Paediatrics, Tbilisi State Medical University, Tbilisi, Georgia
3 Tbilisi State Medical University, Tbilisi, Georgia
4 Department of Epidemiology, Faculty of Medical Sciences, Medical University of Silesia in Katowice, Katowice, Poland

Objectives: Our recent studies showed that in children in the Batumi region, Georgia, underdiagnosis of asthma is 65%, and that not all children with known asthma had a history of allergic disorders. So, we decided to assess the association of known diagnosis of paediatric asthma with asthma-like symptoms and non-respiratory allergic symptoms and diseases using questionnaire-derived data provided by respiratory health survey.

Methods: Subjects of the cross-sectional population-based study were 3,239 urban and 2,113 rural children aged 5-17 years whose respiratory status was assessed using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. For children with a known diagnosis of asthma, the occurrence of respiratory symptoms suggestive of asthmatic tendency and of allergic symptoms and diseases was measured and statistical association of known asthma with the respiratory and allergic symptoms was expressed as odds ratios (OR) and their 95% confidence intervals (95% CI).

Results: Respiratory and all allergic symptoms and diseases, except for eczema, were statistically significantly (p < 0.05) more prevalent in children with asthma than in children without asthma. Based on the distribution of asthma vis-à-vis asthmatic tendency without or with allergic symptoms and allergic diseases the following odds ratios expressing likelihood of asthma were obtained: for asthmatic tendency: OR = 18.09 (95% CI: 11.82-27.68), for any allergic symptom: OR = 6.85 (95% CI: 4.69-10.02), for any allergic disease: OR = 10.75 (95% CI: 7.36-15.70), for asthmatic tendency with coexisting any allergic symptom: OR = 18.94 (95% CI: 12.96-27.68), for asthmatic tendency with coexisting any allergic disease: OR = 25.65 (95% CI: 17.47-37.67), and for asthmatic tendency with coexisting any allergic symptom and allergic disease: OR = 27.02 (95% CI: 18.18-40.15).

Conclusions: The findings support the view that in epidemiological setting questionnaire-based studies on asthma seems to more readily identify cases in children with more severe clinical presentation of the disease and with coexisting allergic disorders, perhaps reflecting diagnostic practices of consulting paediatricians.

Klíčová slova: asthma, allergy, children, underdiagnosis, Georgia

Vloženo: 5. únor 2020; Revidováno: 4. leden 2021; Přijato: 4. leden 2021; Zveřejněno: 31. březen 2021  Zobrazit citaci

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Beridze V, Bakhtadze T, Beridze S, Phagava K, Chkhaidze I, Brożek GM, Zejda JE. Coexistence of asthmatic and non-respiratory allergic symptoms in children of Batumi Region, Georgia: occurrence and association with known diagnosis of asthma. Cent Eur J Public Health. 2021;29(1):23-27. doi: 10.21101/cejph.a6143. PubMed PMID: 33831283.
Sdílet...
Stáhnout citaci
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Zobrazit celý článek

    Reference

    1. Aaron SD, Boulet LP, Reddel HL, Gershon AS. Underdiagnosis and overdiagnosis of asthma. Am J Resp Crit Care Med. 2018;198(8):1012-20. Přejít k původnímu zdroji... Přejít na PubMed...
    2. Brożek G, Lawson J, Shpakou A, Fedortsiv O, Hryshchuk L, Rennie D, et al. Childhood asthma prevalence and risk factors in three Eastern European countries - the Belarus, Ukraine, Poland Asthma Study (BUPAS): an international prevalence study. BMC Pulm Med. 2016;16:11. doi: 10.1186/s12890-016-0172-x. Přejít k původnímu zdroji... Přejít na PubMed...
    3. Beridze V, Abuladze L, Partenadze N, Bakhtadze T, Lawson J, Zejda JE. Childhood asthma in Batumi, Georgia: prevalence and environmental correlates. J Asthma. 2018;55(1):43-9. Přejít k původnímu zdroji... Přejít na PubMed...
    4. Zejda JE, Beridze V, Bakhtadze T, Beridze S, Abuladze L, Partenadze N, et al. Prevalence of and factors associated with underdiagnosis of pediatric asthma in Batumi, Georgia. Allergol Immunopathol (Madr). 2020;48(1):73-7. Přejít k původnímu zdroji... Přejít na PubMed...
    5. Baldacci S, Maio S, Simoni M, Cerrai S, Sarno G, Silvi P, et al. The ARGA study with general practitioners: impact of medical education on asthma/rhinitis management. Respir Med. 2012;106(6):777-85. Přejít k původnímu zdroji... Přejít na PubMed...
    6. Annesi-Maesano I, Sterlin C, Caillaud D, de Blay F, Lavaud F, Charpin D, et al. Factors related to under-diagnosis and under-treatment of childhood asthma in metropolitan France. Multidiscip Respir Med. 2012;7(1):24. doi: 10.1186/2049-6958-7-24. Přejít k původnímu zdroji... Přejít na PubMed...
    7. Zejda JE, Farnik M, Smółka I, Lawson J, Brożek G. Socio-demographic factors related to under-diagnosis of childhood asthma in Upper Silesia, Poland. Ann Agric Environ Med. 2017;24(2):171-5. Přejít k původnímu zdroji... Přejít na PubMed...
    8. Gerald JK, Sun Y, Grad R, Gerald LB. Asthma morbidity among children evaluated by asthma case detection. Pediatrics. 2009;124(5):e927-33. Přejít k původnímu zdroji... Přejít na PubMed...
    9. Richter J, Kral V, Rajnohova Dobiasova L, Svozil V, Pohunek P, Vetvicka V. Prevalence of Asthma Bronchiale in the Czech Republic and its economic burden. Am J Immunol. 2016;12(3):61-68. Přejít k původnímu zdroji...
    10. Skrzypek M, Kowalska M, Kobza J, Wypych A, Czech EM, Niewiadomska E, et al. Community-based survey as a basis for evidence-based public health: children living in Upper Silesian Industrial Zone. Cent Eur J Public Health. 2018;26(3):171-6. Přejít k původnímu zdroji... Přejít na PubMed...
    11. Brożek G, Lawson J, Szumilas D, Zejda J. Increasing prevalence of asthma, respiratory symptoms, and allergic diseases: Four repeated surveys from 1993-2014. Respir Med. 2015;109(8):982-90. Přejít k původnímu zdroji... Přejít na PubMed...
    12. Brożek G, Shpakou A, Lawson J, Zejda J. Rural dwelling and temporal trends in relation to childhood asthma and related conditions in Belarus: a repeated cross-sectional survey. J Agromedicine. 2015;20(3):332-40. Přejít k původnímu zdroji... Přejít na PubMed...
    13. Lai CK, Beasley R, Crane J, Foliaki S, Shah J, Weiland S. Global variation in the prevalence and severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax. 2009;64(6):476-83. Přejít k původnímu zdroji... Přejít na PubMed...
    14. Massoth L, Anderson C, McKinney KA. Asthma and chronic rhinosinusitis: diagnosis and medical management. Med Sci (Basel). 2019;7(4):53. doi: 10.3390/medsci7040053. Přejít k původnímu zdroji... Přejít na PubMed...
    15. Tarasidis GS, Wilson KF. Diagnosis of asthma: clinical assessment. Int Forum Allergy Rhinol. 2015;5 Suppl 1:S23-6. Přejít k původnímu zdroji... Přejít na PubMed...
    16. Schatz M, Rosenwasser L. The allergic asthma phenotype. J Aller Clin Immunol Pract. 2014;2(6):645-8. Přejít k původnímu zdroji... Přejít na PubMed...

    Zpět na obsah