Cent Eur J Public Health 2024, 32(1):25-30 | DOI: 10.21101/cejph.a7818

Association of cardiovascular health and educational status in a screening cohort

Sarah Wernly1, Georg Semmler2, Maria Flamm3, Andreas Völkerer1, Ralf Erkens4, Elmar Aigner5, Christian Datz1, Bernhard Wernly1, 3
1 Department of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical Private University, Oberndorf, Austria
2 Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria
3 Institute of General Practice, Family Medicine and Preventive Medicine, Paracelsus Medical University, Salzburg, Austria
4 Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich Heine University Duesseldorf, Duesseldorf, Germany
5 Clinic I for Internal Medicine, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria

Introduction: The global burden of chronic diseases, including cardiovascular disease, remains a significant public health challenge. The Life's Simple 7 (LS7) score was developed as a tool to evaluate cardiovascular health behaviours and habits and identify high-risk individuals. The present study aimed to assess the distribution of LS7 scores among educational strata.

Methods: The study population consisted of 3,383 asymptomatic individuals screened for colorectal cancer at a single centre in Austria. We split patients into lower (n = 1,055), medium (n = 1,997), and higher (n = 331) education, based on the International Standard Classification of Education (ISCED). Cox regression models were utilized to determine the association between education and mortality over a median follow-up period of 7 years.

Results: Individuals with higher educational status had a significantly higher prevalence of ideal cardiovascular health metrics, as defined by the LS7 score, compared to those with medium and lower educational status: n = 94 (28%) vs. n = 347 (17%) and n = 84 (8%), respectively, (p < 0.001). In the Cox regression analysis, both medium (HR = 0.61, 95% CI: 0.43-0.84, p < 0.001) and higher educational status (HR = 0.44, 95% CI: 0.19-1.01, p = 0.06) were associated with all-cause mortality, as was the LS7.

Conclusion: Our findings highlight a significant association between lower educational status and poorer cardiovascular health, as assessed by LS7, which persisted even after multivariable adjustment. Additionally, both educational status and LS7 were associated with increased mortality, underscoring the significance of our results. These findings have important implications for public health, as screening and prevention strategies may need to be tailored to meet the diverse educational backgrounds of individuals, given the higher prevalence of unhealthy lifestyle behaviours among those with lower educational status.

Keywords: education, Simple 7, cardiovascular health, public health

Received: April 3, 2023; Revised: February 27, 2024; Accepted: February 27, 2024; Published: March 31, 2024  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Wernly S, Semmler G, Flamm M, Völkerer A, Erkens R, Aigner E, et al.. Association of cardiovascular health and educational status in a screening cohort. Cent Eur J Public Health. 2024;32(1):25-30. doi: 10.21101/cejph.a7818. PubMed PMID: 38669154.
Download citation

References

  1. Vaduganathan M, Mensah GA, Turco JV, Fuster V, Roth GA. The global burden of cardiovascular diseases and risk: a compass for future health. J Am Coll Cardiol. 2022 Dec 20;80(25):2361-71. Go to original source... Go to PubMed...
  2. Sacco RL. The new American Heart Association 2020 goal: achieving ideal cardiovascular health. J Cardiovasc Med (Hagerstown). 2011 Apr;12(4):255-7. Go to original source... Go to PubMed...
  3. Díaz-Gutiérrez J, Martínez-González MÁ, Alonso A, Toledo E, Salas-Salvadó J, Sorlí JV, et al. American Heart Association's life simple 7 and the risk of atrial fibrillation in the PREDIMED study cohort. Nutr Metab Cardiovasc Dis. 2023 Jun;33(6):1144-8. Go to original source... Go to PubMed...
  4. Nève G, Wagner J, Knaier R, Infanger D, Klenk C, Carrard J, et al. Ideal Life's Simple 7 score relates to macrovascular structure and function in the healthy population. Nutrients. 2022 Sep 1;14(17):3616. doi: 10.3390/nu14173616. Go to original source... Go to PubMed...
  5. Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, Bäck M, et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2021 Sep 7;42(34):3227-337. Go to original source... Go to PubMed...
  6. Barton P, Andronis L, Briggs A, McPherson K, Capewell S. Effectiveness and cost effectiveness of cardiovascular disease prevention in whole populations: modelling study. BMJ. 2011 Jul 28;343:d4044. doi: 10.1136/bmj.d4044. Go to original source... Go to PubMed...
  7. Chokshi DA, Farley TA. The cost-effectiveness of environmental approaches to disease prevention. N Engl J Med. 2012 Jul 26;367(4):295-7. Go to original source... Go to PubMed...
  8. Fan H, Xu C, Li W, Huang Y, Hua R, Xiong Y, et al. Ideal cardiovascular health metrics are associated with reduced severity of hepatic steatosis and liver fibrosis detected by transient elastography. Nutrients. 2022 Dec 16;14(24):5344. doi: 10.3390/nu14245344. Go to original source... Go to PubMed...
  9. Garg PK, O'Neal WT, Chen LY, Loehr LR, Sotoodehnia N, Soliman EZ, et al. American Heart Association's Life Simple 7 and risk of atrial fibrillation in a population without known cardiovascular disease: the ARIC (Atherosclerosis Risk in Communities) Study. J Am Heart Assoc. 2018 Apr 12;7(8):e008424. doi: 10.1161/JAHA.117.008424. Go to original source... Go to PubMed...
  10. Garg PK, O'Neal WT, Ogunsua A, Thacker EL, Howard G, Soliman EZ, et al. Usefulness of the American Heart Association's Life Simple 7 to predict the risk of atrial fibrillation (from the REasons for Geographic And Racial Differences in Stroke [REGARDS] Study). Am J Cardiol. 2018 Jan 15;121(2):199-204. Go to original source... Go to PubMed...
  11. Chevli PA, Mehta A, Allison M, Ding J, Nasir K, Blaha MJ, et al. Relationship of American Heart Association's Life Simple 7, ectopic fat, and insulin resistance in 5 racial/ethnic groups. J Clin Endocrinol Metab. 2022 May 17;107(6):e2394-404. doi: 10.1210/clinem/dgac102. Go to original source... Go to PubMed...
  12. Ross CE, Wu CL. The Links between education and health. Am Sociol Rev. 1995 Oct;60(5):719-45. Go to original source...
  13. Zajacova A, Lawrence EM. The Relationship between education and health: reducing disparities through a contextual approach. Annu Rev Public Health. 2018 Apr 1;39:273-89. Go to original source... Go to PubMed...
  14. Shen R, Zhao N, Wang J, Guo P, Shen S, Liu D, et al. Association between socioeconomic status and arteriosclerotic cardiovascular disease risk and cause-specific and all-cause mortality: data from the 2005-2018 National Health and Nutrition Examination Survey. Front Public Health. 2022 Nov 22;10:1017271. doi: 10.3389/fpubh.2022.1017271. Go to original source... Go to PubMed...
  15. Wernly S, Semmler G, Völkerer A, Rezar R, Datz L, Radzikowski K, et al. Cardiovascular risk assessment by SCORE2 predicts risk for colorectal neoplasia and tumor-related mortality. J Pers Med. 2022 May 23;12(5):848. doi: 10.3390/jpm12050848. Go to original source... Go to PubMed...
  16. Semmler G, Wernly S, Wernly B, Mamandipoor B, Bachmayer S, Semmler L, et al. Machine learning models cannot replace screening colonoscopy for the prediction of advanced colorectal adenoma. J Pers Med 2021 Sep 29;11(10):981. doi: 10.3390/jpm11100981. Go to original source... Go to PubMed...
  17. Goff DC Jr, Lloyd-Jones DM, Bennett G, Coady S, D'Agostino RB, Gibbons R, et al.; American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014 Jun 24;129(25 Suppl 2):S49-73. Go to original source... Go to PubMed...
  18. Huang PL. A comprehensive definition for metabolic syndrome. Dis Model Mech. 2009 May-Jun;2(5-6):231-7. Go to original source... Go to PubMed...
  19. Schneider SL. The classification of education in surveys: a generalized framework for ex-post harmonization. Qual Quant. 2022 Jun;56(3):1829-66. Go to original source...
  20. Johnson AE, Herbert BM, Stokes N, Brooks MM, Needham BL, Magnani JW. Educational attainment, race, and ethnicity as predictors for ideal cardiovascular health: from the National Health and Nutrition Examination Survey. J Am Heart Assoc. 2022 Jan 18;11(2):e023438. doi: 10.1161/JAHA.121.023438. Go to original source... Go to PubMed...
  21. Alam MT, Echeverria SE, DuPont-Reyes MJ, Vasquez E, Murillo R, Gonzalez T, et al. Educational attainment and prevalence of cardiovascular health (Life's Simple 7) in Asian Americans. Int J Environ Res Public Health. 2021 Feb 4;18(4):1480. doi: 10.3390/ijerph18041480. Go to original source... Go to PubMed...
  22. Adam HS, Merkin SS, Anderson MD, Seeman T, Kershaw KN, Magnani JW, et al. Personal Health Literacy and Life Simple 7: the Multi-Ethnic Study of Atherosclerosis. Am J Health Educ. 2023 Nov 2;54(6):451-62. Go to original source... Go to PubMed...
  23. Nève G, Komulainen P, Savonen K, Hassinen M, Männikkö R, Infanger D, et al. Adherence to Life's Simple 7 is associated with better carotid properties. Atherosclerosis. 2022 Nov;360:21-6. Go to original source... Go to PubMed...
  24. Unkart JT, Allison MA, Criqui MH, McDermott MM, Wood AC, Folsom AR, et al. Life's Simple 7 and peripheral artery disease: the Multi-Ethnic Study of Atherosclerosis. Am J Prev Med. 2019 Feb;56(2):262-270. Go to original source... Go to PubMed...