Central European Journal of Public Health - Nejnovější články
Výsledky 31 až 60 z 114:
Increased macrolide resistance in Streptococcus pneumoniae in Slovakia may be linked to increased macrolide consumption
Peter Kunč, Jaroslav Fábry, Katarina Ištvánková, Martina Neuschlová, Renata Péčová
Cent Eur J Public Health 2025, 33(3):187-192 | DOI: 10.21101/cejph.a8464 
Objectives: Given the widespread use of macrolide antibiotics and growing concerns over antimicrobial resistance, this study aimed to investigate recent trends in macrolide consumption in Slovakia and to determine the corresponding changes in Streptococcus pneumoniae resistance in a paediatric cohort.Methods: We conducted a retrospective analysis of 1,083 nasal swab cultures from children with recurrent respiratory infections and atopy, comparing two distinct 5-year periods: 2008-2012 and 2019-2023. Consumption data was based on the European Centre for Disease Prevention and Control reports. Results: National data confirmed that Slovakia...
Detection and quantification of Sildenafil and Tadalafil in dietary supplements marketed as natural sexual enhancers in Bosnia and Herzegovina
Elma Omeragić, Lejla Jesenković-Habul, Belma Imamović, Mirza Dedić, Amila Turalić, Ervina Bečić
Cent Eur J Public Health 2025, 33(3):181-186 | DOI: 10.21101/cejph.a8397
Objectives: The primary aim of this study is to detect and quantify the presence of Sildenafil (SDF) and Tadalafil (TDF) in dietary supplements marketed as natural sexual enhancers in Bosnia and Herzegovina. Additionally, the study seeks to utilize these findings to inform relevant authorities, enabling further testing in reference laboratories and prompting the necessary actions to remove these adulterated products from the market. Methods: Using high-performance liquid chromatography with diode array detection (HPLC-DAD), 20 samples were analysed for the PDE-5 inhibitors. Results: The analysis revealed that seven of the samples contained...
Current view on HIV-2 – epidemiology, diagnosis and treatment
Dalibor Sedláček
Cent Eur J Public Health 2025, 33(3):176-180 | DOI: 10.21101/cejph.a8631
Human immunodeficiency virus 2 (HIV-2) is a retrovirus related to HIV-1. It is believed to have evolved from the simian immunodeficiency virus (SIV). The disease caused by HIV-2 is manifested by a slower progression compared to HIV-1. Data from West Africa show that 37% to 50% of HIV-2 infected people have undetected or very low viremia and if left untreated, have a much more gradual decline in CD4 T lymphocytes, thus longer survival. However, treatment should not be postponed even in this case, because the course of immune reconstitution inflammatory syndrome (IRIS) in people with HIV-2 is more severe than in HIV-1, and also the year-on-year increase...
The importance of screening asymptomatic patients admitted to healthcare facilities during the COVID-19 pandemic
Petr Smejkal, Filip Hrubý, Anna Horňáková
Cent Eur J Public Health 2025, 33(3):170-175 | DOI: 10.21101/cejph.a8739
Objectives: Screening of asymptomatic patients upon hospital admission became a key strategy to prevent nosocomial transmission of SARS-CoV-2 during the COVID-19 pandemic, particularly in facilities treating immunocompromised patients. Rapid antigen tests (RATs) were widely used due to their speed, but their reliability in detecting potentially infectious individuals remained debated. In parallel, the role of immunosuppression, especially in solid organ transplant (SOT) recipients, as a risk factor for asymptomatic positivity and prolonged viral shedding raised additional concerns. The aim of the study was to evaluate the diagnostic performance of...
Feasibility and acceptability of telemedicine in prenatal care for low-risk pregnancies: a comparative study of remote and in-person approaches in the Czech Republic
Adéla Tefr Faridová, Eva Miletínová, Ondřej Tefr, Jitka Bušková, Beáta Čečetková, Jiří Pecina, Ladislav Krofta, Hynek Heřman
Cent Eur J Public Health 2025, 33(3):163-169 | DOI: 10.21101/cejph.a8520
Objectives: The aim of the study was to evaluate the feasibility and acceptability of remote prenatal care using a smartphone application for women with low-risk pregnancies, and to compare outcomes with standard in-person care. Methods: A prospective observational study was conducted at the Institute for Maternal and Child Care in Podolí, Prague. A total of 225 pregnant women were enrolled: 119 received combined telemedicine and standard in-person follow-ups (W-DF group), while 106 received only standard in-person care (W-PF group). Data on patient satisfaction across various domains of care were collected and analysed. Results: Women...
Inequalities in cervical cancer screening use: results of the Serbian National Health Survey
Dragana Milijašević, Tatjana Tamaš, Sonja Čanković, Snežana Ukropina, Sonja Šušnjević, Tanja Tomašević, Dušan Čanković, Vesna Mijatović Jovanović
Cent Eur J Public Health 2025, 33(3):155-162 | DOI: 10.21101/cejph.a8486
Objectives: Cervical cancer represents a significant public health concern worldwide, particularly among women of reproductive age. According to data from the Cancer Registry of the Republic of Serbia for the year 2022, cervical cancer is the fourth most common cancer in women, with an age-standardized incidence rate (ASIR) of 24.8/100,000 and the fourth leading cause of mortality, with an age-standardized mortality rate (ASMR) of 10.2/100,000. This study aimed to analyse the association between socio-demographic factors, unmet healthcare needs, and cervical cancer screening use among women in Serbia. Methods: Research was conducted as a cross-sectional...
Tobacco use among health professionals: example of one of the largest Czech hospitals, 2012-2023
Eva Králíková, Lenka Štěpánková, Anna Horňáková
Cent Eur J Public Health 2025, 33(2):148-151 | DOI: 10.21101/cejph.a8435
Objectives: The General University Hospital in Prague (GUH) is one of the largest hospitals in the Czech Republic. The prevalence of smoking among hospital staff is monitored as part of its Health Promoting Hospitals (HPH) network membership. Methods: This study employed a cross-sectional design, utilizing anonymous questionnaires distributed to all hospital employees in the years 2012 and 2023 through the hospital's electronic system (response rates 25% and 28%, respectively). Data were analysed using chi-square tests to compare smoking prevalence across time and among subgroups based on profession, sex and age group. Results: The total prevalence...
Beliefs about third-hand smoke and health perceptions of the preschool paediatric patients' parents
Esma Üçüncü, Fatma Gökşin Cihan, Hatice Küçükceran, Sevgi Pekcan, Gökçen Ünal
Cent Eur J Public Health 2025, 33(2):140-147 | DOI: 10.21101/cejph.a8357
Objectives: Millions of children suffer from the harmful effects of tobacco smoking. The aim of this study was to investigate the health perceptions of preschool paediatric patient's parents and their beliefs and attitudes towards third-hand smoke. Methods: This cross-sectional study was conducted with the parents of pre-school paediatric patients. A questionnaire including the socio-demographic information form, the Beliefs About Third-Hand Smoke (BATHS-T) scale and the Perception of Health Scale (PHS) were applied to the participants. Results: Of the 500 parents participating in the study, 74.6% were mothers. Among participants 440 (88.0%) stated...
Potential impact of e-cigarettes on life-years lost from conventional smoking in Ukraine, a replication study
Giorgi Mzhavanadze, Vladimir Dubrovskiy
Cent Eur J Public Health 2025, 33(2):132-139 | DOI: 10.21101/cejph.a8382
Objectives: Smoking remains a significant public health concern in Ukraine. Recent efforts to combat smoking have shown some progress, but Ukraine's current approach largely overlooks the potential benefits of harm reduction strategies. Concurrently, the use of e-cigarettes has been on the rise among Ukrainian adults. Our study aims to estimate the potential impact of e-cigarettes on reducing the mortality rate associated with cigarette smoking in Ukraine. Methods: We conducted a replication study using a dynamic population simulation model initially developed for the US. We ran simulations for 210 e-cigarette scenarios, varying assumptions on how...
Alcohol use and COVID-19: three-year impact for the Czech Republic
Vladimír Rogalewicz, Benjamin Petruželka, Jaroslav Vacek, Michal Miovský, Ingeborg Rossow, Carolin Kilian, Jakob Manthey, Miroslav Barták
Cent Eur J Public Health 2025, 33(2):122-131 | DOI: 10.21101/cejph.a8410
Objectives: The aim of the study was to describe alcohol consumption and its changes in the Czech Republic during the period of governmental restrictions related to the COVID-19 pandemic. To this goal, an overview of the governmental measures that may have affected alcohol consumption was compiled from various sources (mostly media reports). Methods: The paper analyses three surveys where the group from Charles University, Prague, participated in design and execution: the European Study Group on Alcohol use and COVID-19 (ESAC) convenience online survey that (in Czechia) took place at the onset of the COVID-19 pandemic in Europe, in April through June...
Retrospective evaluation of measures in the field of occupational health services during the COVID-19 epidemic
Matyáš Fošum, Marie Nakládalová, Ladislav Štěpánek
Cent Eur J Public Health 2025, 33(2):116-121 | DOI: 10.21101/cejph.a8626
Objectives: In the Czech Republic, employers and employees are bound by legal regulations that ensure occupational health and safety. These regulations are based on international conventions of the International Labour Organization and directives of the European Parliament and Council and have long been incorporated into Czech legislation. During the COVID-19 epidemic, emergency and crisis measures led to a limitation of occupational health examinations (OHEs) in the Czech Republic, which represented a significant disruption of the occupational health and safety system. The aim of the study was to assess the impact of these measures in order to find...
COVID-19 as the occupational disease in employees of the University Hospital Ostrava
Silvie Ostřížková, Daniela Vybíralová, Zdeňka Hajduková, Pavlína Kuchařová, Terezie Lichovníková, Renata Zlotkowska, Hana Tomášková
Cent Eur J Public Health 2025, 33(2):108-115 | DOI: 10.21101/cejph.a8428
Objectives: COVID-19 disease, which has caused a global pandemic, poses significant threat to the healthcare system as healthcare workers (HCW) are at an elevated risk of contracting the disease and being temporarily removed from their regular duties. This study analyses and evaluates a cohort of employees at the University Hospital Ostrava (UHO) who applied for the recognition of COVID-19 as an occupational disease. Methods: The disease characteristics and risk factors for severe cases of COVID-19 were analysed for all 474 claimants who applied for recognition of an occupational disease during the reporting period (March 2020 to November 2022) and...
Preventive effect of precautionary lowered exposure or adaptation of nanomaterial workers?
Daniela Pelclová, Tomáš Navrátil, Jaroslav Schwarz, Vladimír Ždímal, Štěpánka Dvořáčková, Pavlína Klusáčková, Štěpánka Vlčková, Andrea Rössnerová
Cent Eur J Public Health 2025, 33(2):101-107 | DOI: 10.21101/cejph.a8524
Objectives: Nanotechnology is a fast-growing field in both science and industry. However, experimental studies brought warning data concerning the negative effect of engineered nanoparticle exposure leading to oxidative stress, inflammation, decreased immune cell viability, and genotoxicity. The consequences of human exposure may appear with decades of latency. Therefore, more data is needed to identify the hazardous effects of nanoparticles. Exposure should be under control and biomarkers of effect are urgently searched. Methods: Exposures of researchers working with nanocomposites were measured in yearly intervals for 5 years and biomarkers of oxidative...
Body mass index limitation of overweight and obesity in Czech military personnel
Blanka Kupsová, Vladimír Pavlík, Jana Fajfrová, Václav Šafka, Petr Lašák, Jan M. Horáček
Cent Eur J Public Health 2025, 33(2):95-100 | DOI: 10.21101/cejph.a8529
Objectives: The first aim of this cross-sectional study was to reveal the prevalence of overweight and obesity among Czech military personnel (CMP). The second aim was to compare accuracy of the body mass index (BMI) classification with the body fat percentage (BF%), waist circumference (WC), and visceral fat area (VFA). BMI is a commonly used method to assess obesity, but its accuracy in reflecting body composition, especially in physically fit individuals, has been questioned. Methods: Data were collected from six military units in the Czech Republic. Soldiers underwent anthropometric assessments including height, weight, WC, BF%, and VFA using the...
Incidence of tuberculosis in the city of Cordoba and its relationship with areas in need of social transformation: a study from 2015 to 2021
Emilia García Rivera, Carmen Aguilar Romero, Rafael Ruiz Montero, Juan José López Moyano, Mohamed Farouk Allam, Álvaro Serrano Ortiz, Inmaculada Salcedo Leal
Cent Eur J Public Health 2025, 33(2):88-94 | DOI: 10.21101/cejph.a8452
Objectives: In 2022, about 17% of Andalusian population lived in disadvantaged areas, which accounted for 21% of tuberculosis (TB) cases. This concentration of cases resulted in TB rates in these areas being higher than both the regional and national averages. The aim of the present study was to understand the behaviour of TB in terms of person, time, and place in the city of Cordoba during the period 2015-2021 and its association with areas in need of social transformation (ANST). Methods: A retrospective observational analytical study was conducted on cases reported to the Andalusian Epidemiological Surveillance System (Spanish acronym SVEA). Membership...
Colorectal cancer screening to identify undiagnosed hepatitis C in an Austrian cohort
Hannah Hofer, Sebastian Bachmayer, Hannah Oberthaler, Georg Semmler, Sarah Wernly, Sophie Gensluckner, Lea Maria Stangassinger, Bernhard Wernly, Ursula Huber-Schönauer, Bernhard Paulweber, Elmar Aigner, Gertie Janneke Oostingh, Christian Datz
Cent Eur J Public Health 2025, 33(2):83-87 | DOI: 10.21101/cejph.a8270
Objectives: Hepatitis C virus (HCV) infection remains a significant public health concern despite the introduction of direct acting antiviral agents. To reach the World Health Organization (WHO) goal of eliminating viral hepatitis as a public health threat by 2030, adequate screening strategies and early diagnosis are crucial. This study aimed to determine the prevalence of HCV infection in an Austrian cohort and assess the feasibility of incorporating HCV screening into colorectal screening programmes. Methods: The study enrolled 1,894 asymptomatic individuals during a colorectal screening programme with a mean age of 57 (± 7 years) years. Sera...
Rising incidence of Mycoplasma pneumoniae pneumonias in a tertiary paediatric centre: implications for antibiotic therapyShort communication
Luboš Bača, Lea Slováková, Jitka Vočková, Karolína Doležalová
Cent Eur J Public Health 2025, 33(1):77-79 | DOI: 10.21101/cejph.a8434
Objectives: The aim of this study is to determine the incidence of Mycoplasma pneumoniae pneumonia (MPP) in children and adolescents in Prague, Czech Republic, between January and July 2024, and to compare the findings with data from the preceding period. Methods: A retrospective analysis of data of paediatric patients at our single tertiary care facility was conducted. Two distinct patient cohorts were subjected to analysis: the first comprising individuals who had been hospitalised between January 2019 and July 2024, and the second consisting of outpatients who had been treated during the periods of January to July 2023 and January to July...
Possibilities of influencing the function of the deep stabilization system by exercising for low back pain
Elena Žiaková, Nina Sládeková, Jana Havlová
Cent Eur J Public Health 2025, 33(1):71-76 | DOI: 10.21101/cejph.a8199
Objectives: Chronic back pain is the most common cause of incapacity for work. The purpose of the study was to determine the effectiveness for activating the function of the deep stabilization system (DSS) in patients with chronic low back pain. Methods: The effectiveness of three different methods was compared: Pilates method (PM), dynamic neuromuscular stabilization and balance aids on deep stabilization system function and pain perception in the lumbar spine. The group consisted of 75 patients. Results: The results show differences in the effectiveness of the methods depending on the observed characteristics. The least significant differences were...
Impact of injury location and type of traffic participants on the outcome of traffic accidents in Montenegro
Damir Peličić, Mirjana Nedović Vuković
Cent Eur J Public Health 2025, 33(1):65-70 | DOI: 10.21101/cejph.a8241
Objectives: The aim of this study was to examine the frequency of fatalities in injuries in traffic accidents in Montenegro, identify contributing risk factors, and determine the most vulnerable participants in these accidents. Methods: The research was designed as a retrospective descriptive study. Participants were people admitted to the Urgent Centre of Clinical Centre of Montenegro due to injuries in traffic accidents that resulted in serious bodily injury or death in the period from 2011-2020. We presented data using descriptive statistics. The square test was used to examine the association between the outcome of traffic injury with sex, age,...
Beliefs about third-hand tobacco smoke among university employees: a cross-sectional study
Ilgin Timarci, Asya Banu Babaoğlu, Mustafa Tözün, Kaan Sözmen
Cent Eur J Public Health 2025, 33(1):57-64 | DOI: 10.21101/cejph.a8366
Objectives: This study aimed to evaluate the beliefs about third-hand tobacco smoke (THS) among administrative and academic staff at a university. THS is a residual pollutant from tobacco smoke that lingers on surfaces and poses health risks, particularly to children. The study also aimed to understand these beliefs in relation to socio-demographic factors. Methods: A cross-sectional survey was conducted with 332 university employees aged 18 and over. Data were collected between September and December 2023 through face-to-face and online questionnaires. The survey included the Beliefs About Third-hand Smoke (BATHS-T) Scale and questions on socio-demographic...
The role of conservative treatment in regional variations of 30-day acute myocardial infarction mortality: a case of the Czech Republic
Ivo Hlaváč, Matěj Opatrný
Cent Eur J Public Health 2025, 33(1):49-56 | DOI: 10.21101/cejph.a8462
Objectives: The aim of the study was to analyse the role of conservative treatment and regional differences in 30-day hospital mortality for acute myocardial infarction (AMI) patients in the Czech Republic. Methods: Using administrative data from Czech health insurance companies for 2018-2020, we employed a probit model to examine factors influencing mortality across 13 complex cardiovascular centres, calculating average marginal effects to ensure interpretable results. Results: Conservative treatment was associated with a 4.7 percentage point increase in 30-day mortality compared to percutaneous coronary intervention (PCI) treatment (95% CI: 3.6-5.7)....
Prevalence of dietary supplement use among the military population: a systematic review and meta-analysis
Roghayeh Molani-Gol, Maryam Rafraf, Beitullah Alipour
Cent Eur J Public Health 2025, 33(1):36-48 | DOI: 10.21101/cejph.a8321
Objectives: The aim of the study was to evaluate widespread dietary supplements (DSs) use among the military population. There is no recent study to comprehensively evaluate the prevalence of DS use among the military population. Therefore, this systematic review and meta-analysis aimed to present an overview and estimate of the overall prevalence of DSs use among the military population. Methods: PubMed, Scopus, Web of Science, and Google Scholar databases were searched up to September 2023 using relevant keywords. All original articles written in English evaluating the prevalence of DSs use among the military population were eligible for this study....
Oral health of pregnant women and possibilities for improving oral health prophylaxis in Lithuania
Jolita Juknienė, Gabrielė Šimėnaitė, Birutė Mockevičienė
Cent Eur J Public Health 2025, 33(1):30-35 | DOI: 10.21101/cejph.a8459
Objectives: The aim of the study was to identify potential areas for improvement in the prevention of oral diseases in pregnant women by assessing their oral care habits and awareness regarding oral health. Methods: An original, anonymous, web-based survey was conducted among women at any stage of pregnancy. The survey consisted of 23 questions regarding oral care habits, knowledge about oral health of mother and child, general and oral health changes, and attendance of oral healthcare services during pregnancy. The data analysis was performed using IBM SPSS 27.0 version software. Descriptive statistics, Chi-square and Wilcoxon signed-rank tests were...
Health literacy and socioeconomic characteristics of young people in Serbia and their influence on reproductive health and sexual behaviour
Milena Maričić, Goran Stojanović, Zlata Rajković Pavlović, Jovana Milosavljević, Melanija Tepavčević, Kristijan Jovanović, Nikoleta Janićijević, Milos Stepović
Cent Eur J Public Health 2025, 33(1):24-29 | DOI: 10.21101/cejph.a8336
Objectives: Having adequate level of health literacy is a very powerful tool of improving health. "Emerging adulthood" is described as a period between age of 18-25 years, characterized by changing life circumstances, developing personality and exploring possibilities. The aim of this study was to establish the relationship between health literacy and socioeconomic status of young adults in Serbia and their individual influence on the reproductive health and sexual behaviour. Methods: This research was conducted as observational, cross-sectional study. We used STOFHLA to assess the health literacy level of young people and general information questionnaire...
Association of depressive symptoms and social determinants of health in medical students of four countries - Czechia, Iran, Kenya, and Venezuela
Anna Zimovjanová, Frederick Murunga Wekesah, Fatemeh Dehghani Firouzabadi, Jan Brož, Jana Urbanová, Jeffrey I. Mechanick, Natalia Sulbarán, Andrea Medina, Geraldo A. Maranhao Neto, Ramfis Nieto-Martinez, Masih A. Babagoli, Maritza Torres, Monika Kunzová, Martin Pešl, José Medina, Eunice Ugel, Hesam Jahandideh, Maryam Roomiani, Niloofar Deravi, Amirhossein Poopak, Alireza Esteghamati, Juan P. González-Rivas
Cent Eur J Public Health 2025, 33(1):17-23 | DOI: 10.21101/cejph.a8222
Objectives: Medical students experience worse psychological well-being than the general population. Social determinants of health (SDOH) relate to conditions in which people live, work, and age and significantly influence mental health. This study examines the association between depressive symptoms and SDOH in medical students from four countries: Czechia, Iran, Kenya, and Venezuela. Methods: An online cross-sectional survey was conducted in the spring of 2022. The questionnaire focused on depressive symptoms (using a validated psychiatric scale DASS-21 to assess mental health) and various SDOHs. Results: A total of 2,033 medical students participated...
New treatment strategies in HIV/AIDS infection and the impact of treatment adherence on the quality of life of people living with HIV
Dalibor Sedláček, Sam Hofman, Jiří Frei, Marek Malý
Cent Eur J Public Health 2025, 33(1):12-16 | DOI: 10.21101/cejph.a7382
Objective: The aim of the study was the assessment of adherence to antiretroviral (ARV) treatment in a population of people living with HIV (PWH), improving the awareness of PWH, drawing attention to the risk of developing HIV drug resistance and subsequent treatment failure. Methods: The basic cohort consisted of PWH followed up long-term at the HIV centre of the University Hospital Pilsen. Adherence to treatment was assessed by ARV levels. Nucleoside analogs were determined in urine by high pressure liquid chromatography (HPLC), in relation to clinical data, viral load (HIV RNA), and absolute CD4 and CD8 T cell counts. To assess mental and physical...
Association between complex exposure to cadmium and mercury and atopic dermatitis in elementary school students: analysis using data from the Korean National Environmental Health Survey (KoNEHS) Cycle 4
Kiook Baek
Cent Eur J Public Health 2025, 33(1):3-11 | DOI: 10.21101/cejph.a8437
Objectives: Atopic dermatitis (AD) is a common allergic disease with potential links to environmental pollutants, including heavy metals. This study investigates the association between co-exposure to cadmium and mercury and AD among Korean children. Methods: Data from the fourth cycle of the Korean National Environmental Health Survey (KoNEHS) included 736 elementary school students. Urinary cadmium and mercury levels were measured, and their association with lifetime prevalence of AD was analysed using logistic regression, weighted quantile sum (WQS) regression, quantile g-computation (QGC), and Bayesian kernel machine regression (BKMR). Confounders...
EditorialExploring Public Health Sciences: Insights from Slovak and Czech Research
Erik Dorko, Kvetoslava Rimárová
Cent Eur J Public Health 2024, 32(Suppl):S3
The field of public health sciences continues to evolve rapidly, driven by cutting-edge research addressing pressing medical challenges and improving clinical practices. The studies published from Slovakia and the Czech Republic in this CEJPH Supplementum 2024 exemplify this progress, offering valuable insights into a diverse array of public health topics. The issue highlights key contributions from these impactful studies, underscoring their relevance to global and regional quality of public health.
Socioeconomic inequalities and their impact on the health of seniors 65+Exploring Public Health Sciences: Insights from Slovak and Czech Research
Jitka Vacková, Kvetoslava Rimárová, Lenka Motlová, Renata Švestková, Erik Dorko, Ivana Chloubová, Radek Vistořín, Kristýna Hellerová, Lesia Shuranová, Eva Fichtnerová, Markéta Bendová
Cent Eur J Public Health 2024, 32(Suppl):S85-90 | DOI: 10.21101/cejph.a8280
Objectives: The main aim of the article is to indicate how selected socioeconomic factors contribute to the selected characteristics of the subjectively perceived health of seniors 65+ living in the Czech Republic. Methods: Data collection took place in the Czech Republic from 27 January 2020 to 14 February 2020. The total number of interviews carried out in the research was 1,172, from a representative quota sample of seniors from the senior population living in the Czech Republic. Questionnaires were distributed in the form of PAPI interviews. Results: The assessment of subjective social status increases with education and employment (these three...
Analysis of COVID-19 patient outcomes with molnupiravir treatment and the role of risk factors: a single-centre retrospective descriptive studyExploring Public Health Sciences: Insights from Slovak and Czech Research
Ondrej Zahornacký, Štefan Porubčin, Alena Rovňáková, Pavol Jarčuška, Dária Semenovová, Paulína Kubalcová, Erik Dorko, Kvetoslava Rimárová
Cent Eur J Public Health 2024, 32(Suppl):S104-110 | DOI: 10.21101/cejph.a8398
Objective: This study aims to describe the outcomes of COVID-19 patients treated with molnupiravir and to explore the associations with various risk factors. Methods: We conducted a single-centre, descriptive, retrospective study without a comparison group. Results: Out of 141 patients, 70 (49.7%) required follow-up outpatient care. In the subgroup of 66 (46.8%) hospitalized patients, 28 (19.9%) developed interstitial viral pneumonia, with 6 (4.3%) deaths. Unvaccinated patients had a higher incidence of pneumonia (p = 0.020), and obesity was a significant risk factor for both pneumonia (p = 0.001) and mortality (p = 0.011). Patients over 60 years (p...